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Merck
모든 사진(1)

문서

C0399

Sigma-Aldrich

Cromolyn sodium salt

≥95%

동의어(들):

Cromoglycate, Cromoglycic acid

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About This Item

Linear Formula:
C23H14O11Na2
CAS Number:
Molecular Weight:
512.33
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥95%

형태

powder

주관자

Sanofi Aventis

SMILES string

[Na].OC(COc1cccc2OC(=CC(=O)c12)C(O)=O)COc3cccc4OC(=CC(=O)c34)C(O)=O

InChI

1S/C23H16O11.Na.H/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30;;/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30);;

InChI key

UXMUBZWVLQEMRB-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Cromolyn sodium is a mast stabilizer, which is used to treat allergies. It is a bischromone and functions as a non-steroidal anti-inflammatory drug. It inhibits the release of histamines from mast cells.

애플리케이션

Cromolyn sodium salt has been used to block mast cell activation and to inhibit histamine secretion from rodent peritoneal mast cells. It has also been used to stabilize mast cells.

생화학적/생리학적 작용

Cromolyn blocks the release of histamine and other pro-inflammatory mediators from mast cells.

특징 및 장점

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Zuyi Weng et al.
PloS one, 7(3), e33805-e33805 (2012-04-04)
Mast cells are immune cells critical in the pathogenesis of allergic, but also inflammatory and autoimmune diseases through release of many pro-inflammatory cytokines such as IL-8 and TNF. Contact dermatitis and photosensitivity are skin conditions that involve non-immune triggers such
Neuropeptide Initiated Mast Cell Activation by Transcutaneous Electrical Acupoint Stimulation of Acupoint LI4 in Rats
Chen LZ, et al.
Scientific Reports, 8(1), 13921-13921 (2018)
Mast cells and histamine are triggering the NF-kappaB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation
Nizamutdinova IT, et al.
Aging (Albany. NY.), 8(11), 3065-3065 (2016)
Osmo Kari et al.
Current allergy and asthma reports, 12(3), 232-239 (2012-03-03)
About 30% of people suffer from allergic symptoms, and 40% to 80% of them have eye symptoms. Atopic conjunctivitis is divided into seasonal allergic conjunctivitis and perennial allergic conjunctivitis. The treatment of seasonal allergic conjunctivitis is simple: antihistamines, anti-inflammatory agents
Mehra Haghi et al.
The AAPS journal, 14(1), 79-86 (2011-12-29)
Two microparticle systems containing disodium cromoglycate (DSCG) alone or with polyvinyl alcohol (DSCG/PVA) were produced via spray drying and compared in terms of their physicochemical characteristics, aerosol performance and drug uptake across a pulmonary epithelial cell line (Calu-3), cultured under

문서

Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.

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