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Merck
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주요 문서

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B7775

Sigma-Aldrich

[Hyp3]-Bradykinin

≥97% (HPLC), suitable for cell culture

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C50H73N15O12
CAS Number:
37642-65-2
Molecular Weight:
1076.21
MDL number:
MFCD00076259
UNSPSC 코드:
12352200
PubChem Substance ID:
329773302
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제품명

[Hyp3]-Bradykinin, ≥97% (HPLC)

분석

≥97% (HPLC)

양식

powder

기술

cell culture | mammalian: suitable

색상

white

UniProt 수납 번호

P06767

저장 온도

−20°C

SMILES string

N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N2C[C@H](O)C[C@H]2C(=O)NCC(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)N[C@@H](Cc5ccccc5)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

InChI

1S/C50H73N15O12/c51-32(15-7-19-56-49(52)53)45(73)64-22-10-18-38(64)47(75)65-27-31(67)25-39(65)43(71)58-26-40(68)59-34(23-29-11-3-1-4-12-29)41(69)62-36(28-66)46(74)63-21-9-17-37(63)44(72)61-35(24-30-13-5-2-6-14-30)42(70)60-33(48(76)77)16-8-20-57-50(54)55/h1-6,11-14,31-39,66-67H,7-10,15-28,51H2,(H,58,71)(H,59,68)(H,60,70)(H,61,72)(H,62,69)(H,76,77)(H4,52,53,56)(H4,54,55,57)/t31-,32+,33+,34+,35+,36+,37+,38+,39+/m1/s1

InChI key

JXRLHZCEMXTCBN-DIBGMJQNSA-N

유전자 정보

rat ... Tac1(24806)

Amino Acid Sequence

Arg-Pro-Hyp-Gly-Phe-Ser-Pro-Phe-Arg

생화학적/생리학적 작용

[Hyp3]-Bradykinin is a bradykinin receptor agonist used to differentiate bradykinin receptors in various cells, tissues and species.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
051M1680V
051M1680
060M1517
099K1571
069K1200

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문서 라이브러리 방문

[Structures and functions of kininogen and kinin hydroxyproline derivatives as multi-functional proteins].
H Kato
[Rinsho ketsueki] The Japanese journal of clinical hematology, 30(10), 1690-1693 (1989-10-01)
R Dengler et al.
FEBS letters, 262(1), 111-114 (1990-03-12)
The recently isolated, naturally occurring peptide hormones [Hyp3]-bradykinin and [Hyp3]-Lys-bradykinin were investigated for their agonist activity on solubilized binding sites from human fibroblasts. Both ligands competed with [3H]bradykinin binding in a dose-dependent fashion with potencies similar to bradykinin (BK) and
Y Matsumura et al.
Agents and actions, 29(3-4), 172-180 (1990-03-01)
We have recently found presence of a high concentration of a novel type of kinin, hydroxyprolyl3-bradykinin (Hyp3-BK) in human tumor ascites in addition to conventional bradykinin (BK). Because of their potential physiological activity, it is of interest to know how
D Regoli et al.
Life sciences, 55(10), 735-749 (1994-01-01)
Bradykinin, desArg9BK, some agonist analogues and several antagonists have been tested in isolated organs in order to identify bradykinin B2 receptor subtypes. The initial pharmacological characterization was made in the rabbit jugular vein and the guinea pig ileum, two widely
M Hecker et al.
British journal of pharmacology, 111(1), 238-244 (1994-01-01)
1. To examine the possibility that angiotensin-converting enzyme (ACE) inhibitors modulate the action of bradykinin at the receptor level, their effect on the dilator response to bradykinin was studied in the isolated saline-perfused heart of the rabbit. 2. Continuous infusion
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