90834

Bradykinin acetate salt

analytical standard

• 실험식(Hill 표기법): C₅₀H₇₃N₁₅O₁₁ · xC₂H₄O₂
• CAS Number: 6846-03-3
• Molecular Weight: 1060.21 (free base basis)
• EC Number: 227-781-2
• UNSPSC 코드: 85151701
• NACRES: NA.24

속성

• Grade: analytical standard
• Quality Level: 100
• 분석: ≥98.0% (HPLC)
• 유통기한: limited shelf life, expiry date on the label
• 분석물 화학적 분류: peptides
• 기술: HPLC: suitable
• 불순물: ≤10 wt. % water
• 색상: white
• 응용 분야: food and beverages
• 형식: neat
• 저장 온도: 2-8°C
• InChI: 1S/C50H73N15O11/c51-32(16-7-21-56-49(52)53)45(72)65-25-11-20-39(65)47(74)64-24-9-18-37(64)43(70)58-28-40(67)59-34(26-30-12-3-1-4-13-30)41(68)62-36(29-66)46(73)63-23-10-19-38(63)44(71)61-35(27-31-14-5-2-6-15-31)42(69)60-33(48(75)76)17-8-22-57-50(54)55/h1-6,12-15,32-39,66H,7-11,16-29,51H2,(H,58,70)(H,59,67)(H,60,69)(H,61,71)(H,62,68)(H,75,76)(H4,52,53,56)(H4,54,55,57)/t32-,33-,34-,35-,36-,37-,38-,39-/m0/s1
• InChI key: QXZGBUJJYSLZLT-FDISYFBBSA-N

설명

Amino Acid Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg

애플리케이션

Bradykinin acetate salt may be used as a precursor for the preparation of bradykinin (BK) prior to its determination from acidic aqueous solutions by electromembrane extraction (EME) followed by analysis using high performance liquid chromatography (HPLC) with ultraviolet (UV) detector.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

생화학적/생리학적 작용

Bradykinin is a pro-inflammatory peptide that acts through G-protein-coupled receptors. It activates sphingolipid metabolism. Fibroblasts treated with bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content. The peptide also increases ceramide cellular content by rapidly mobilizing neutral glycolipids. Bradykinin plays an important role in the regulation of fluid and electrolyte balance, smooth muscle contraction, vasodilation and capillary permeability. The bradykinin potentiators, which possess no bradykinin activity themselves, enhance the activity of bradykinin.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable