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Merck
모든 사진(2)

주요 문서

A2126

Sigma-Aldrich

Acetyl-β-methylcholine bromide

≥99%

동의어(들):

Methacholine bromide

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크기 선택

100 G
₩582,509

₩582,509


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100 G
₩582,509

About This Item

Linear Formula:
CH3CO2CH(CH3)CH2N(CH3)3Br
CAS Number:
Molecular Weight:
240.14
EC Number:
MDL number:
UNSPSC 코드:
12352103
PubChem Substance ID:
NACRES:
NA.25

₩582,509


구입 가능 여부는 고객센터에 문의하십시오.

벌크 견적 요청

분석

≥99%

양식

powder

mp

147-149 °C (lit.)

저장 온도

−20°C

SMILES string

[Br-].CC(C[N+](C)(C)C)OC(C)=O

InChI

1S/C8H18NO2.BrH/c1-7(11-8(2)10)6-9(3,4)5;/h7H,6H2,1-5H3;1H/q+1;/p-1

InChI key

MMVPLEUBMWUYIB-UHFFFAOYSA-M

유전자 정보

human ... CHRM3(1131)

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애플리케이션

Acetyl-β-methylcholine bromide (methylcholine bromide, methacholine bromide, Mch), a muscarinic acetylcholine receptor agonist, may be used in studies that involve the indentification, characterization and mechanism of action of muscarinic acetylcholine receptors. Mch may be used as a reference material in procedures used to detect or quantify its presence.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

M J van der Schans et al.
Journal of chromatography. A, 735(1-2), 387-393 (1996-05-31)
Solutions of histamine and methacholine bromide in different matrices for diagnostic purposes were analyzed for stability and quality control using capillary electrophoresis. Histamine (2,[4-imidazolyl]ethylamine) [CAS No. 51-45-6] was determined using a 0.1 M Tris-borate buffer of pH 8.3 with 5.10(-5)
David C Hornigold et al.
British journal of pharmacology, 138(7), 1340-1350 (2003-04-25)
1. We have examined possible mechanisms of cross-talk between the G(q/11)-linked M(3) muscarinic acetylcholine (mACh) receptor and the G(i/o)-linked M(2) mACh receptor by stable receptor coexpression in Chinese hamster ovary (CHO) cells. A number of second messenger (cyclic AMP, Ins(1,4,5)P(3))
John T Fisher et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 18(6), 711-713 (2004-02-24)
The presence of multiple muscarinic acetylcholine receptor (mAChR) subtypes in the heart and lung, combined with the lack of mAChR subtype-selective ligands, have complicated the task of identifying the mAChR subtypes mediating cardiac slowing (bradycardia) and airway narrowing (bronchoconstriction) due
M Yamada et al.
Nature, 410(6825), 207-212 (2001-03-10)
Members of the muscarinic acetylcholine receptor family (M1-M5) have central roles in the regulation of many fundamental physiological functions. Identifying the specific receptor subtype(s) that mediate the diverse muscarinic actions of acetylcholine is of considerable therapeutic interest, but has proved
Linda Jeeva Kumari Henry et al.
Biochemical and biophysical research communications, 526(3), 833-840 (2020-04-11)
Peroxisome proliferator-activated receptor gamma (PPARγ) is a multifaceted ligand-activated transcription factor that regulates inflammatory responses in asthma pathophysiology. The present study corroborates PPARγ-mediated anti-asthmatic action of the flavonoid, galangin (norizalpinin). In silico molecular interactions reveal that galangin formed three H-bonds

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