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Merck
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문서

PHR1828

Supelco

Eucalyptol (cineole)

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Eucalyptol, 1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane, 1,8-Cineole, 1,8-Epoxy-p-menthane

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About This Item

실험식(Hill 표기법):
C10H18O
CAS Number:
Molecular Weight:
154.25
Beilstein:
105109
EC Number:
MDL number:
UNSPSC 코드:
12352212
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to Ph. Eur. Y0000176
traceable to USP 1268900

API family

cineole

CofA

current certificate can be downloaded

포장

pkg of 500 mg

기술

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.457 (lit.)

bp

176-177 °C (lit.)

mp

1-2 °C (lit.)

density

0.921 g/mL at 25 °C (lit.)

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

SMILES string

C[C@]12CC[C@H](CC1)C(C)(C)O2

InChI

1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3/t8-,10+

InChI key

WEEGYLXZBRQIMU-WAAGHKOSSA-N

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일반 설명

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Eucalyptol, a natural monoterpene, is a component of many medicinally active aromatic plants, such as eucalyptus, cardamom, thyme, rosemary, and ginger. It exhibits subduing effect on mucus hypersecretion, non-purulent rhinosinusitis, and asthma.

애플리케이션

This pharmaceutical secondary standard can also be used as follows:

  • Simultaneous estimation of menthol and eucalyptol in their combined marketed analgesic formulations by high-performance thin layer chromatography (HPTLC) procedure
  • The development of an International Conference on Harmonization (ICH) guideline validated HPTLC method for the determination of α-pinene and eucalyptol in plants from the Lamiaceae family
  • Headspace sorptive extraction (HSSE) of seven monoterpenes for their gas chromatography and mass spectrometry (GC-MS) based quantitative analysis from different honey samples
  • Screening and estimation of eucalyptol in a polyherbal formulation using an HPTLC-based technique

분석 메모

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

각주

To see an example of a Certificate of Analysis for this material enter LRAB9507 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

추천 제품

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

픽토그램

FlameExclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Flam. Liq. 3 - Skin Sens. 1

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

125.6 °F - closed cup

Flash Point (°C)

52 °C - closed cup


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시험 성적서(COA)

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이미 열람한 고객

A validated HPTLC method for estimation of Eucalyptol in polyherbal formulations
Patra KC, et al.
Der Pharmacia Lettre, 2, 316-320 (2010)
Development of high-performance thin-layer chromatography (HPTLC) validated method for simultaneous quantification of eucalyptol and ?-pinene in lamiaceae plants
Foudah AI, et al.
Journal of Pharmaceutical Research International, 31, 1-11 (2019)
J I Cacho et al.
Journal of chromatography. A, 1399, 18-24 (2015-05-11)
Headspace sorptive extraction (HSSE) was used to preconcentrate seven monoterpenes (eucalyptol, linalool, menthol, geraniol, carvacrol, thymol and eugenol) for separation by gas chromatography and mass spectrometry (GC-MS). Three commercially available coatings for the stir bars, namely Polydimethylsiloxane (PDMS), polyacrilate (PA)

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