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Merck
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문서

PHR1034

Supelco

Lidocaine

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

2-Diethylamino-N-(2,6-dimethylphenyl)acetamide, Lignocaine, Xylocaine

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About This Item

실험식(Hill 표기법):
C14H22N2O
CAS Number:
Molecular Weight:
234.34
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to BP 727
traceable to Ph. Eur. L0595000
traceable to USP 1366002

API family

lidocaine

CofA

current certificate can be downloaded

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

InChI key

NNJVILVZKWQKPM-UHFFFAOYSA-N

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일반 설명

Lidocaine is a drug, which serves as a potential candidate in the treatment of cardiac arrhythmias.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Lidocaine is a local anesthetic drug that can exhibit pronounced antiarrhythmic and anticonvulsant effects. It is known as a central nervous system depressant and shows sedative, analgesic and anticonvulsant properties.

애플리케이션

Lidocaine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
Lidocaine may be used as an internal standard in the determination of perhexiline in human serum samples using gas liquid chromatography (GLC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

생화학적/생리학적 작용

Na+ channel blocker; class IB antiarrhythmic that is rapidly absorbed after parenteral administration.

분석 메모

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAC0142 in the slot below. This is an example certificate only and may not be the lot that you receive.

추천 제품

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

관련 제품

제품 번호
설명
가격

분석 컬럼

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Simultaneous determination of tolperisone and lidocaine by high performance liquid chromatography
Liawruangrath S, et al.
Journal of Pharmaceutical and Biomedical Analysis, 26(5-6), 865-872 (2001)
High-performance liquid chromatographic method for the simultaneous determination of lidocaine and its N-dealkylated metabolites in plasma
Nation.LR, et al.
Journal of Chromatography. B, Biomedical Applications, 162, 466-473 (1979)
Stability indicating HPLC method for the estimation of oxycodone and lidocaine in rectal gel
Gebauer MG, et al.
International Journal of Pharmaceutics, 223(1-2), 49-54 (2001)
A rapid method for the determination of perhexiline in serum using gas-liquid chromatography
CooperHDJ and Turnell CD
Annals of Clinical Biochemistry, 17, 155-158 (1980)
Development and validation of RP-HPLC method for cetrimonium bromide and lidocaine determination.
Malenovic A, et al.
Il Farmaco (Societa Chimica Italiana : 1989), 60(2), 157-161 (2005)

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