์ฝ˜ํ…์ธ ๋กœ ๊ฑด๋„ˆ๋›ฐ๊ธฐ
Merck
๋ชจ๋“  ์‚ฌ์ง„(1)

์ฃผ์š” ๋ฌธ์„œ

P8074

Sigma-Aldrich

TWEENยฎ 80

BioXtra, viscous liquid

๋™์˜์–ด(๋“ค):

TWEENยฎ 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80

๋กœ๊ทธ์ธ์กฐ์ง ๋ฐ ๊ณ„์•ฝ ๊ฐ€๊ฒฉ ๋ณด๊ธฐ

ํฌ๊ธฐ ์„ ํƒ

100 ML
โ‚ฉ96,121
500 ML
โ‚ฉ218,631

โ‚ฉ96,121


์ถœ๊ณ  ๊ฐ€๋Šฅ์ผ2025๋…„ 4์›” 08์ผ์„ธ๋ถ€์‚ฌํ•ญ


๋ฒŒํฌ ๊ฒฌ์  ์š”์ฒญ

ํฌ๊ธฐ ์„ ํƒ

๋ณด๊ธฐ ๋ณ€๊ฒฝ
100 ML
โ‚ฉ96,121
500 ML
โ‚ฉ218,631

About This Item

CAS Number:
MDL number:
UNSPSC ์ฝ”๋“œ:
12161900
NACRES:
NA.21

โ‚ฉ96,121


์ถœ๊ณ  ๊ฐ€๋Šฅ์ผ2025๋…„ 4์›” 08์ผ์„ธ๋ถ€์‚ฌํ•ญ


๋ฒŒํฌ ๊ฒฌ์  ์š”์ฒญ

์„ค๋ช…

non-ionic

Quality Level

์ œํ’ˆ ๋ผ์ธ

BioXtra

์–‘์‹

viscous liquid

๋ถ„์ž๋Ÿ‰

micellar avg mol wt 79,000
average mol wt 1310

๊ตฌ์„ฑ

Oleic acid, ~70% (balance primarily linoleic, palmitic, and stearic acids)

์‘์ง‘ ๋ฒˆํ˜ธ

60

๊ธฐ์ˆ 

DNA extraction: suitable
RNA extraction: suitable
cell culture | mammalian: suitable
protein purification: suitable

๋ถˆ์ˆœ๋ฌผ

โ‰ค0.025% Phosphorus (P)

๋ฌด๊ธฐ ์ž”๋ฅ˜๋ฌผ

<0.1%

CMC

0.012ย mM (20-25ยฐC)

์ „์ด ์˜จ๋„

cloud point 65ย ยฐC

density

1.06ย g/mLย at 25ย ยฐC

์Œ์ด์˜จ ๋ฏธ๋Ÿ‰๋ฌผ

chloride (Cl-): <0.05%
sulfate (SO42-): <0.05%

์–‘์ด์˜จ ๋ฏธ๋Ÿ‰๋ฌผ

Al: <0.0005%
Ca: <0.001%
Cu: <0.0005%
Fe: <0.0005%
K: <0.005%
Mg: <0.0005%
NH4+: <0.05%
Na: <0.05%
Pb: <0.001%
Zn: <0.0005%

HLB

15

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

์œ ์‚ฌํ•œ ์ œํ’ˆ์„ ์ฐพ์œผ์‹ญ๋‹ˆ๊นŒ? ๋ฐฉ๋ฌธ ์ œํ’ˆ ๋น„๊ต ์•ˆ๋‚ด

์ผ๋ฐ˜ ์„ค๋ช…

["TWEEN"] 80 is a polyethylene sorbitol ester, broadly used in biochemical applications like solubilizing proteins, isolating nuclei from cells in culture, and growing tubercle bacilli. It is also useful in emulsifying and dispersing substances in medicinal and food products. TWEEN 80 acts as an active drying agent in ice cream.

์• ํ”Œ๋ฆฌ์ผ€์ด์…˜

["TWEEN"] 80 has been used:
  • to dissolve rapamycin (RAPA) for immunosuppressive treatment to perform in vivo studies in mice
  • to dissolve remodelin and remodelin Fluor to assess remodelin toxicity in vivo and small molecule dosing
  • to prepare assay medium for the microbiological assay for total folate

๋ฒ•์  ์ •๋ณด

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (ยฐF)

>235.4 ยฐF - closed cup

Flash Point (ยฐC)

> 113 ยฐC - closed cup

๊ฐœ์ธ ๋ณดํ˜ธ ์žฅ๋น„

Eyeshields, Gloves


๊ฐ€์žฅ ์ตœ์‹  ๋ฒ„์ „ ์ค‘ ํ•˜๋‚˜๋ฅผ ์„ ํƒํ•˜์„ธ์š”:

์‹œํ—˜ ์„ฑ์ ์„œ(COA)

Lot/Batch Number

์ ํ•ฉํ•œ ๋ฒ„์ „์„ ์ฐพ์„ ์ˆ˜ ์—†์œผ์‹ ๊ฐ€์š”?

ํŠน์ • ๋ฒ„์ „์ด ํ•„์š”ํ•œ ๊ฒฝ์šฐ ๋กœํŠธ ๋ฒˆํ˜ธ๋‚˜ ๋ฐฐ์น˜ ๋ฒˆํ˜ธ๋กœ ํŠน์ • ์ธ์ฆ์„œ๋ฅผ ์ฐพ์„ ์ˆ˜ ์žˆ์Šต๋‹ˆ๋‹ค.

์ด ์ œํ’ˆ์„ ์ด๋ฏธ ๊ฐ€์ง€๊ณ  ๊ณ„์‹ญ๋‹ˆ๊นŒ?

๋ฌธ์„œ ๋ผ์ด๋ธŒ๋Ÿฌ๋ฆฌ์—์„œ ์ตœ๊ทผ์— ๊ตฌ๋งคํ•œ ์ œํ’ˆ์— ๋Œ€ํ•œ ๋ฌธ์„œ๋ฅผ ์ฐพ์•„๋ณด์„ธ์š”.

๋ฌธ์„œ ๋ผ์ด๋ธŒ๋Ÿฌ๋ฆฌ ๋ฐฉ๋ฌธ

์ด๋ฏธ ์—ด๋žŒํ•œ ๊ณ ๊ฐ

Slide 1 of 5

1 of 5

Polysorbate 80 United States Pharmacopeia (USP) Reference Standard

USP

1547969

Polysorbate 80

TWEEN&#174; 20 BioXtra, viscous liquid

Sigma-Aldrich

P7949

TWEENยฎ 20

TWEEN&#174; 80 (Polysorbate) EMPROVE&#174; ESSENTIAL, Ph. Eur., JP, NF

SAFC

8.17061

TWEENยฎ 80 (Polysorbate)

Polysorbate 80 OmniPur&#174;

Millipore

9490-OP

Polysorbate 80

TWEEN&#174; 80 protein grade detergent, 10% solution, sterile-filtered, for immunoprecipitation and for the solubilization of membrane-bound proteins

Millipore

655207

TWEENยฎ 80

Geoffrey D Keeler et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 26(1), 173-183 (2017-09-26)
The devastating neurodegenerative disease multiple sclerosis (MS) could substantially benefit from an adeno-associated virus (AAV) immunotherapy designed to restore a robust and durable antigen-specific tolerance. However, developing a sufficiently potent and lasting immune-regulatory therapy that can intervene in ongoing disease
Joel Selkrig et al.
Scientific reports, 8(1), 10646-10646 (2018-07-15)
In animals, commensal microbes modulate various physiological functions, including behavior. While microbiota exposure is required for normal behavior in mammals, it is not known how widely this dependency is present in other animal species. We proposed the hypothesis that the
Brian Hassett et al.
mAbs, 10(1), 166-176 (2017-10-12)
Fusion protein and monoclonal antibody-based tumor necrosis factor (TNF) inhibitors represent established treatment options for a range of inflammatory diseases. Regulatory authorities have outlined the structural characterization and clinical assessments necessary to establish biosimilarity of a new biotherapeutic product with
Sen Zhu et al.
Nature communications, 9(1), 500-500 (2018-02-07)
BMI1, a polycomb group (PcG) protein, plays a critical role in epigenetic regulation of cell differentiation and proliferation, and cancer stem cell self-renewal. BMI1 is upregulated in multiple types of cancer, including prostate cancer. As a key component of polycomb
Sen Zhu et al.
Oncogene, 39(1), 17-29 (2019-08-30)
B lymphoma Mo-MLV insertion region 1 (BMI1) has been reported to be an oncoprotein. BMI1 represses tumor suppressors to promote cell proliferation, epithelial-mesenchymal transition (EMT), and cancer progression. Although it is known that the expression of BMI1 is increased in

๋ฌธ์„œ

A complete reversed phase HPLC-ELSD workflow, including sample preparation for the analysis of Polysorbate 80 in a monoclonal antibody formulation.

์งˆ๋ฌธ

1โ€“3 / 3 ์งˆ๋ฌธ ย 
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 ๋‹ต๋ณ€
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      ๋„์›€์ด ๋˜์—ˆ์Šต๋‹ˆ๊นŒ?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 ๋‹ต๋ณ€
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      ๋„์›€์ด ๋˜์—ˆ์Šต๋‹ˆ๊นŒ?

  3. Whatโ€™s the concentration of P8074-100ml Tween 80? Thank you.

    1 ๋‹ต๋ณ€
    1. This Tween 80 product is the pure form, it has not been diluted in water or other aqueous buffers. The composition of this surfactant is available in the PROPERTIES section of the product detail page and is approximately 70 % oleic acid with the balance being primarily linoleic, palmitic, and stearic acids.

      ๋„์›€์ด ๋˜์—ˆ์Šต๋‹ˆ๊นŒ?

ํ›„๊ธฐ

ํ‰์  ๊ฐ’ ์—†์Œ

ํ™œ์„ฑ ํ•„ํ„ฐ

์ž์‚ฌ์˜ ๊ณผํ•™์žํŒ€์€ ์ƒ๋ช… ๊ณผํ•™, ์žฌ๋ฃŒ ๊ณผํ•™, ํ™”ํ•™ ํ•ฉ์„ฑ, ํฌ๋กœ๋งˆํ† ๊ทธ๋ž˜ํ”ผ, ๋ถ„์„ ๋ฐ ๊ธฐํƒ€ ๋งŽ์€ ์˜์—ญ์„ ํฌํ•จํ•œ ๋ชจ๋“  ๊ณผํ•™ ๋ถ„์•ผ์— ๊ฒฝํ—˜์ด ์žˆ์Šต๋‹ˆ๋‹ค..

๊ณ ๊ฐ์ง€์›ํŒ€์œผ๋กœ ์—ฐ๋ฝ๋ฐ”๋ž๋‹ˆ๋‹ค.