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59924

Sigma-Aldrich

Polysorbate 80

tested according to Ph. Eur.

동의어(들):

TWEEN® 80, Polysorbatum 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80

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100 G
₩68,513
1 KG
₩259,028

₩68,513

출고 가능일2025년 4월 02일세부사항

벌크 견적 요청
모든 사진(1)

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보기 변경
100 G
₩68,513
1 KG
₩259,028

About This Item

CAS Number:
9005-65-6
MDL number:
MFCD00082107
UNSPSC 코드:
12161900
NACRES:
NA.21

₩68,513

출고 가능일2025년 4월 02일세부사항

벌크 견적 요청

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

200

vapor pressure

<1 mmHg ( 20 °C)

설명

non-ionic

양식

liquid

분자량

average mol wt 79,000

응집 번호

60

refractive index

n20/D 1.472 (lit.)

CMC

0.012

전이 온도

cloud point 65 °C

density

1.064 g/mL at 25 °C (lit.)

HLB

15

응용 분야

pharmaceutical (small molecule)

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

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관련 카테고리

일반 설명

Polysorbate 80 is a surfactant.[1] Polysorbates are a combination of oleic esters of sorbitol and sorbitanes with polyethylene glycol chains.[2]

애플리케이션

Polysorbate 80 has been used in drug (rapamycin) treatment[3][4] and to study the effect of rapamycin on osteolysis and tumor growth.[3] It has also been used in the preparation of spray-dried emulsions and to study antibacterial efficacy.[5]

생화학적/생리학적 작용

Polysorbates is used as emulsifiers, dissolving agents and stabilizer for essential oils, topical application and medical infusions including intravenous, subcutaneous or intramuscular administration.[2]

법적 정보

TWEEN is a registered trademark of Croda International PLC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
BCCM4005
BCCL9053
BCCL8063
BCCL7067
BCCL4464

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COA 검색

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문서 라이브러리 방문

이미 열람한 고객

Slide 1 of 4

1 of 4

TWEEN&#174; 80 from non-animal source

Sigma-Aldrich

P6224

TWEEN® 80

TWEEN&#174; 80 solution 10%, low peroxide

Sigma-Aldrich

P8192

TWEEN® 80 solution

TWEEN&#174; 80 suitable for cell culture, suitable for insect cell culture, viscous liquid

Sigma-Aldrich

P4780

TWEEN® 80

Polysorbate 20

Sigma-Aldrich

W291501

Polysorbate 20

Priya N O Kasimbeg et al.
Journal of pharmaceutical sciences, 108(1), 155-161 (2018-10-14)
Characterizing protein aggregates in the presence of silicone oil is a long standing challenge for the pharmaceutical industry. Silicone oil is often used as a lubricant in devices that deliver and store therapeutic protein products and has been linked to
Enhancing the antibacterial efficacy of isoeugenol by emulsion encapsulation
Nielsen CK, et al.
International Journal of Food Microbiology, 229, 7-14 (2016)
Nilsel Okudan et al.
Brain research bulletin, 165, 81-89 (2020-10-04)
Statins are cholesterol lowering drugs that decrease the risk of cardiovascular events, but they are related with a few unfavorable symptoms in skeletal muscle including myopathy, and mild to moderate fatigue. Additionally, there has been discrepancies about the impacts of
Relationship between Polysorbate 80 solubilization descriptors and octanol-water partition coefficients of drugs
Alvarez Nunez FA and Yalkowsky SH
International Journal of Pharmaceutics, 200(2), 217-222 (2000)
Osteolysis and pain due to experimental bone metastases are improved by treatment with rapamycin
Abdelaziz DM, et al.
Breast Cancer Research and Treatment, 143(2), 227-237 (2014)
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질문

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 답변

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 답변

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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