B018
WB-4101 hydrochloride
analytical standard
동의어(들):
2-[(2,6-Dimethoxyphenoxyethyl)aminomethyl]-1,4-benzodioxane hydrochloride
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100 MG
₩185,644
About This Item
실험식(Hill 표기법):
C19H23NO5 · HCl
CAS Number:
Molecular Weight:
381.85
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
추천 제품
Grade
analytical standard
Quality Level
기술
HPLC: suitable
gas chromatography (GC): suitable
형식
neat
SMILES string
Cl.COc1cccc(OC)c1OCCNCC2COc3ccccc3O2
InChI
1S/C19H23NO5.ClH/c1-21-17-8-5-9-18(22-2)19(17)23-11-10-20-12-14-13-24-15-6-3-4-7-16(15)25-14;/h3-9,14,20H,10-13H2,1-2H3;1H
InChI key
KAHMEWANVDFFCQ-UHFFFAOYSA-N
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애플리케이션
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
가장 최신 버전 중 하나를 선택하세요:
K Ichishima et al.
British journal of pharmacology, 161(1), 193-206 (2010-08-20)
Volume-regulated anion channels (VRACs) play an important role in cell-volume regulation. alpha(1)-Adrenoceptor stimulation by phenylephrine (PE) suppressed the hypotonic activation of VRAC current in mouse ventricular cells and regulatory volume decrease (RVD) was also absent in PE-treated cells. We examined
W-X Yuan et al.
Neuroscience, 158(4), 1616-1624 (2008-12-11)
Activation of the descending noradrenergic system inhibits nociceptive transmission in the spinal cord. Although both alpha(1)- and alpha(2)-adrenoceptors in the spinal cord are involved in the modulation of nociceptive transmission, it is not clear how alpha(1)-adrenoceptors regulate excitatory and inhibitory
Josie R T Silva et al.
The journal of pain : official journal of the American Pain Society, 12(1), 51-60 (2010-06-18)
We evaluated the effectiveness of intrathecal antagonists of α1- (WB4101) and α2- (idazoxan) adrenoceptors and serotonergic (methysergide), opioid (naloxone), muscarinic (atropine), GABA(A) (bicuculline) and GABA(B) (phaclofen) receptors in blocking 2- or 100-Hz electroacupuncture (EA)-induced analgesia (EAIA) in the rat tail-flick
Laura Fumagalli et al.
European journal of medicinal chemistry, 58, 184-191 (2012-11-06)
Unichiral 8-substituted analogues of 2-[(2-(2,6-dimethoxyphenoxy)ethyl)aminomethyl]-1,4-benzodioxane (WB4101) were synthesized and tested for binding affinity at cloned human α(1a)-, α(1b)-and α(1d)-adrenoreceptor (α(1a)-, α(1b)-and α(1d)-AR) and at native rat 5-HT(1A) receptor and for antagonist affinity at α(1A)-, α(1B)-and α(1D)-AR and at α(2A/D)-AR. Among
Fernando H F Alves et al.
Brain research, 1295, 119-126 (2009-08-19)
The insular cortex (IC) has been reported to modulate the cardiac parasympathetic activity of the baroreflex in unanesthetized rats. However, which neurotransmitters are involved in this modulation is still unclear. In the present study, we evaluated the possible involvement of
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