모든 사진(4)
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5 G
₩196,301
10 G
₩309,981
25 G
₩615,192
About This Item
Linear Formula:
NH2CH2CH2CN · ½ (HO2CCH=CHCO2H)
CAS Number:
Molecular Weight:
128.13
Beilstein:
3573532
EC Number:
MDL number:
UNSPSC 코드:
12352202
PubChem Substance ID:
NACRES:
NA.77
추천 제품
생물학적 소스
synthetic (organic)
Quality Level
분석
≥98% (TLC)
양식
powder
mp
177 °C (dec.) (lit.)
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
SMILES string
NCCC#N.NCCC#N.OC(=O)\C=C\C(O)=O
InChI
1S/C4H4O4.2C3H6N2/c5-3(6)1-2-4(7)8;2*4-2-1-3-5/h1-2H,(H,5,6)(H,7,8);2*1-2,4H2/b2-1+;;
InChI key
NYMXYZMHOZAPHQ-SEPHDYHBSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
3-Aminopropionitrile fumarate salt has been used as a lysyl oxidase (LOX) inhibitor:
- to inhibit collagen cross-linking during microtissue formation and culture[1]
- in LIM domain only 1 (LMO1)- or vector-expressing BE2C neuroblastoma cell line in transwell migration and invasion assay[2]
- in lysyl oxidase (LOX) activity assay[3]
- to study requirement of LOX activity for inducing hypoxia-inducible factor (HIF)2A-dependent stiffness in mouse organoids[4]
생화학적/생리학적 작용
3-Aminopropionitrile (β-Aminopropionitrile (BAPN)) functions as an irreversible inhibitor of lysyl oxidase (LOX), an enzyme involved in collagen cross-linking.[1]
In mammals, metabolism of 3-aminopropionitrile leads to release of cyanide ions. Metabolic activity is localized in the microsomal fraction of the liver, and is believed to proceed through a free-radical pathway.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Repr. 1B
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
개인 보호 장비
Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
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Force-driven evolution of mesoscale structure in engineered 3D microtissues and the modulation of tissue stiffening
Zhao R, et al.
Biomaterials, 35(19), 5056-5064 (2014)
LMO1 synergizes with MYCN to promote neuroblastoma initiation and metastasis
Zhu Shizhen, et al.
Cancer Cell, 32(3), 310-323 (2017)
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