T4625

Thiamine hydrochloride

reagent grade, ≥99% (HPLC)

• 동의어(들): Aneurine hydrochloride, Vitamin B₁ hydrochloride
• 실험식(Hill 표기법): C₁₂H₁₇ClN₄OS · HCl
• CAS Number: 67-03-8
• Molecular Weight: 337.27
• Beilstein: 3851771
• EC Number: 200-641-8
• MDL number: MFCD00012780
• UNSPSC 코드: 12352209
• eCl@ss: 34058006
• PubChem Substance ID: 24900057
• NACRES: NA.26

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• Grade: reagent grade
• 분석: ≥99% (HPLC)
• 양식: powder
• 기술: HPLC: suitable
• 색상: white
• mp: 250 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL, clear, colorless
• SMILES string: CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]
• InChI: 1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
• InChI key: DPJRMOMPQZCRJU-UHFFFAOYSA-M

설명

일반 설명

Thiamine is a water-soluble vitamin-B complex. Structurally, it possesses a five-membered thiazolium ring and a six-membered amino-pyrimidine ring connected by a methyl group. Thiamine is naturally available in fruits, vegetables, poultry, eggs.[1]

애플리케이션

Thiamine hydrochloride has been used as a vitamin supplement to the holidic medium[2] and in bacterial growth medium.[3][4]

생화학적/생리학적 작용

Thiamine is an essential coenzyme in carbohydrate metabolism.[5] Deficiency of thiamine causes beriberi, a neurological and cardiovascular disease.[1] Thiamine is administered in case of deficiency, either due to reduced intake or synthesis.[5][1] Congenital defect in the thiamine transporter gene SLC19A2 causes thiamine-responsive megaloblastic anemia syndrome (TRMA). Thiamine mimics acetylcholine in brain and possible exerts a role in Alzheimer′s disease.[1] Thiamine deficiency in ruminants causes polioencephalomalacia.[5]

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)