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Merck
모든 사진(1)

문서

90527

Supelco

Hydroxychloroquine sulfate

analytical standard

동의어(들):

7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate

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About This Item

실험식(Hill 표기법):
C18H26ClN3O · H2SO4
CAS Number:
Molecular Weight:
433.95
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

분석

≥95.0% (HPLC)

유통기한

limited shelf life, expiry date on the label

포장

pkg of 50 mg

기술

HPLC: suitable
gas chromatography (GC): suitable

불순물

≤1.0% water

색상

white to off-white

응용 분야

forensics and toxicology
pharmaceutical (small molecule)
veterinary

형식

neat

저장 온도

2-8°C

SMILES string

OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12

InChI

1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

InChI key

JCBIVZZPXRZKTI-UHFFFAOYSA-N

유전자 정보

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일반 설명

Hydroxychloroquine Sulfate (Hydroxychloroquine Sulphate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.

애플리케이션

Hydroxychloroquine Sulfate can be used as an analytical standard for the determination of the analyte in pharmaceutical formulations, and biological samples by various analytical techniques.

생화학적/생리학적 작용

Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

High-performance liquid chromatographic assay for hydroxychloroquine and three of its major metabolites, desethylhydroxychloroquine, desethylchloroquine and bidesethylchloroquine, in human plasma
Brown RR, et al.
Journal of Chromatography. B, Biomedical Applications, 377(11), 454-459 (1986)
Analysis of blood and urine samples for hydroxychloroquine and three major metabolites by high-performance liquid chromatography with fluorescence detection
Williams SB, et al.
Journal of Chromatography. B, Biomedical Applications, 433(11), 197-206 (1988)
Seminars in Arthritis and Rheumatism, 43(2), 264-272 (2013)
A rapid and reliable method for the quantitation of hydroxychloroquine in serum using turbulent flow liquid chromatography-tandem mass spectrometry
Fuzery AK, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 421 (2013)
Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole blood
Charlier B,et al.
Biomedical Chromatography, 32(8), e4258-e4258 (2018)

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