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Merck
모든 사진(1)

주요 문서

89640

Sigma-Aldrich

Toluidine Blue

8.74% (ZN (THEORY)), for microscopy (Hist., Vit.)

동의어(들):

Tolonium chloride; Basic Blue 17

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크기 선택

5 G
₩68,411
25 G
₩213,861

₩68,411


예상 입고일2025년 4월 07일세부사항


벌크 견적 요청

크기 선택

보기 변경
5 G
₩68,411
25 G
₩213,861

About This Item

실험식(Hill 표기법):
C15H16ClN3S · 0.5ZnCl2
CAS Number:
Molecular Weight:
373.97
색상 지수 번호:
52040
Beilstein:
4068052
MDL number:
UNSPSC 코드:
12171500
PubChem Substance ID:
NACRES:
MA.02

₩68,411


예상 입고일2025년 4월 07일세부사항


벌크 견적 요청

Grade

for microscopy (Hist., Vit.)

Quality Level

분석

8.74% (ZN (THEORY))

양식

powder or crystals

기술

microbe id | staining: suitable

색상

green to very dark green

solubility

methanol: 0.01 g/10 mL, blue to very deep blue

εmax

≥800 at 621-636 nm in water

적합성

suitable for microscopy

응용 분야

diagnostic assay manufacturing
hematology
histology

저장 온도

room temp

SMILES string

[Cl-].[Cl-].Cl[Zn]Cl.Cc1cc2N=C3C=CC(\C=C3Sc2cc1N)=[N+](\C)C.Cc4cc5N=C6C=CC(\C=C6Sc5cc4N)=[N+](\C)C

InChI

1S/2C15H15N3S.4ClH.Zn/c2*1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13;;;;;/h2*4-8,16H,1-3H3;4*1H;/q;;;;;;+2/p-2

InChI key

DAQXTSXITPUGRG-UHFFFAOYSA-L

일반 설명

Toluidine blue (C.l. 52040) is a diaminothiazine dye.It is also known as TBO, tolonium chloride, and toluidine blue O.

애플리케이션

Toluidine Blue is suitable for use in the following applications:
  1. to demonstrate amyloid; DNA in plant material, mast cells, Nissl substance, nuclei, and sulfatides
  2. in metachromatic staining of sulfated mucins and related materials
  3. as staining agent to identify the development and accumulation of the cartilage matrix, proteoglycans for isolation and culture of mesenchymal stem cells from mouse compact bone.
  4. staining of mucins in water-miscible resins and of nucleic acids in epoxy resins(1)

생화학적/생리학적 작용

Toluidine Blue is a basic thiazine metachromatic dye, which is used for selectively staining acidic tissue components such as carboxylates, sulfates, and phosphate radicals.It is found to have an affinity for nucleic acids and therefore binds to the nuclear material of tissues with a high DNA and RNA content.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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Journal of tissue engineering and regenerative medicine, 11(7), 1974-1985 (2015-11-10)
Locally applied bisphosphonates, such as zoledronate, have been shown in several studies to inhibit peri-implant bone resorption and recently to enhance peri-implant bone formation. Studies have also demonstrated positive effects of hydroxyapatite (HA) particles on peri-implant bone regeneration and an
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The intermingling of regenerated nerve fibers inside nerve grafts is the main reason for mismatched nerve fibers. This is one of the key factors affecting limb function recovery after nerve injury. Previous research has shown that the accuracy of axon
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Plant science : an international journal of experimental plant biology, 286, 37-48 (2019-07-14)
In this work, a non-metallicolous and a metallicolous population of S. paradoxa were exposed to copper excess and fungal elicitation, and investigated for phytohormone production and cytological alterations. Under the stress applied separately and in combination, S. paradoxa plants varied

질문

1–2 / 2 질문  
  1. Are there any instructions on how to mix Toluidine Blue powder (89640) into a staining solution?

    1 답변
    1. Toluidine Blue is used in various staining procedures, and preparation may vary depending on the specific procedure. For staining frozen sections, aqueous solutions with concentrations ranging from 0.3% to 1% can be used. Additionally, a 0.5% dye in 20% alcohol is suitable for frozen sections. Other solutions may require a specific pH or special preparation.

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  2. What does C.l. 52040 mean?

    1 답변
    1. The C.I. number is the Colour Index number. This number is globally recognized and is assigned to Dyes and Pigments by the Americal Association of Textile Chemists and Colourists (AATCC) established in 1924. This compound is assigned a C.I. number of 52040. Please see the link below to learn more about the Colour Index program:
      https://colour-index.com/

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