410225

Glycine

≥98.5%, ACS reagent for peptide synthesis

• 동의어(들): Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Linear Formula: NH₂CH₂COOH
• CAS Number: 56-40-6
• Molecular Weight: 75.07
• Beilstein: 635782
• EC Number: 200-272-2
• MDL number: MFCD00008131
• UNSPSC 코드: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24865701
• NACRES: NA.21

속성

• 제품명: Glycine, ACS reagent, ≥98.5%
• Grade: ACS reagent
• Quality Level: 200
• 분석: ≥98.5%
• 양식: powder, crystals or granules
• 불순물: H₂SO₄, passes test (darkened); Hydrolyzable subsances, passes test
• 무기 잔류물: ≤0.1%
• 색상: white
• pKa(25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• 음이온 미량물: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• 양이온 미량물: NH₄⁺: ≤0.005%; heavy metals: ≤0.002% (by ICP)
• 응용 분야: peptide synthesis
• 작용기: amine; carboxylic acid
• SMILES string: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• InChI key: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• 유전자 정보: rat ... Grin2a(24409)

설명

일반 설명

Glycine is the simplest amino acid building block.

애플리케이션

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents.[1] It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.[2]

생화학적/생리학적 작용

Glycine is a non-essential amino acid.[3] Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors.[4] Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.[3]

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)