추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity purified immunoglobulin
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
rat
제조업체/상표
Chemicon®
기술
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... PPP1R9B(84687)
특이성
Spinophilin
면역원
Synthetic peptide from rat Spinophilin.
애플리케이션
Anti-Spinophilin Antibody detects level of Spinophilin & has been published & validated for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Neuronal & Glial Markers
Synapse & Synaptic Biology
Neuronal & Glial Markers
Western blot: 0.05 - 0.1 μg/mL using ECL on rat brain lysate. Reacts with a band of ~140 kDa.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
물리적 형태
Affinity purified immunoglobulin. Liquid in 0.02M phosphate buffer containing 0.25M NaCl, pH 7.6 with 0.1% sodium azide.
저장 및 안정성
Maintain at 2-8°C in undiluted for up to 6 months after date of receipt.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Eva M Verdugo-Sivianes et al.
Oncotarget, 8(62), 105196-105210 (2017-12-30)
The scaffold protein Spinophilin (Spinophilin, PPP1R9B) is one of the regulatory subunits of phosphatase-1 (PP1), directing it to distinct subcellular locations and targets. The loss of Spinophilin reduces PP1 targeting to pRb, thereby maintaining higher levels of phosphorylated pRb. Spinophilin
Kisho Obi-Nagata et al.
Science advances, 9(23), eade5973-eade5973 (2023-06-09)
Human genetics strongly support the involvement of synaptopathy in psychiatric disorders. However, trans-scale causality linking synapse pathology to behavioral changes is lacking. To address this question, we examined the effects of synaptic inputs on dendrites, cells, and behaviors of mice
Steven R Boikess et al.
The European journal of neuroscience, 28(10), 2099-2107 (2008-12-03)
Structural studies have shown that chronic regimens of psychostimulants increase dendritic spine number in the rat striatum. The present study used Western blotting and radioimmunocytochemistry to examine psychostimulant-induced changes in the levels of spinophilin, a protein found abundantly in dendritic
Melanie J Grubisha et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(49) (2021-12-02)
Normally, dendritic size is established prior to adolescence and then remains relatively constant into adulthood due to a homeostatic balance between growth and retraction pathways. However, schizophrenia is characterized by accelerated reductions of cerebral cortex gray matter volume and onset
Purificacion Estevez-Garcia et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 19(14), 3925-3935 (2013-06-05)
The genomic region 17q21 is frequently associated with microsatellite instability and LOH in cancer, including gastric and colorectal carcinomas. This region contains several putative tumor suppressor genes, including Brca1, NM23, prohibitin, and spinophilin (Spn, PPP1R9B, neurabin II). The scaffold protein
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