324696

Elastase Substrate I, Colorimetric

A specific chromogenic substrate for human neutrophil elastase.

• 동의어(들): Elastase Substrate I, Colorimetric
• 실험식(Hill 표기법): C₂₇H₃₈N₆O₉
• CAS Number: 70967-90-7
• Molecular Weight: 590.63
• MDL number: MFCD00077137
• UNSPSC 코드: 12352200
• NACRES: NA.54

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 형태: lyophilized
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated
• solubility: water: 1 mg/mL
• 배송 상태: ambient
• 저장 온도: −20°C
• InChI: 1S/C27H38N6O9/c1-15(2)23(30-18-8-10-19(11-9-18)33(40)41)26(38)31-25(37)20-7-6-14-32(20)27(39)17(4)29-24(36)16(3)28-21(34)12-13-22(35)42-5/h8-11,15-17,20,23,30H,6-7,12-14H2,1-5H3,(H,28,34)(H,29,36)(H,31,37,38)/t16-,17-,20-,23-/m0/s1
• InChI key: JWYKDZIEIWGSBN-OSAZLGQLSA-N

설명

일반 설명

A specific chromogenic substrate for human neutrophil elastase (K_cat/K_m = 120,000 vs. 2700 for pancreatic elastase). Cleavage can be monitored at ~410 nm. Sold on the basis of substrate content.

Specific chromogenic substrate for human neutrophil elastase (k_cat/K_m = 120,000 versus pancreatic elastase: k_cat/K_m = 2,700). Cleavage can be monitored at 410 nm using ε = 8,800.

생화학적/생리학적 작용

Cell permeable: no

Kcat/Km = 120,000 vs. 2700 for pancreatic elastase

Primary Target
Chromogenic substrate for human neutrophil elastase

Product does not compete with ATP.

Reversible: no

경고

Toxicity: Standard Handling (A)

서열

MeOSuc-Ala-Ala-Pro-Val-pNA

물리적 형태

Lyophilized from a solution containing 90 mg D-mannitol and 10 mg substrate.

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Barrett, A.J., et al. 1989. Biochim. J.260, 259.
Nakajima, K., et al. 1979. J. Biol. Chem.254, 4027.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable