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Merck
모든 사진(1)

주요 문서

17-218

Sigma-Aldrich

Ras Activation Assay Kit

동의어(들):

Ras Activity Assay

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About This Item

UNSPSC 코드:
12161503
eCl@ss:
32161000
NACRES:
NA.84
가격 및 재고 정보를 현재 이용할 수 없음 고객지원팀으로 연락바랍니다.

제조업체/상표

Upstate®

Quality Level

기술

activity assay: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

유전자 정보

human ... MRAS(22808)

일반 설명

Muscle RAS oncogene homolog (MRAS) plays a key role in cardiovascular diseases. The MRAS gene codes for a member of the ras superfamily of GTP-binding proteins. MRAS is found in all tissues, particularly in the cardiovascular system. It is involved in signal transduction, including cell growth and differentiation.[1]

포장

Kit capacity: 30 assays

성분

Ras Assay Reagent (Raf-1 RBD, agarose) (Cat.# 14-278)

Anti-Ras, clone RAS10 (Cat.# 05-516)

100X GTPγS, 10mM (Cat.# 20-176)

100X GDP, 100mM (Cat.# 20-177)

Mg2+ Lysis/Wash Buffer, 5X (Cat.# 20-168)

품질

This kit precipitated Ras-GTP from HeLa cell lysates that had been loaded with GTPγS. The precipitated Ras-GTP was detected by western immunoblot using 1μg/ml anti-Ras, clone RAS10

결합

Replaces: SGT435

법적 정보

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

픽토그램

CorrosionEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1

Storage Class Code

10 - Combustible liquids


시험 성적서(COA)

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문서 라이브러리 방문

J Kim et al.
The Journal of biological chemistry, 276(22), 19102-19110 (2001-03-23)
AMP-activated protein kinase (AMPK) is tightly regulated by the cellular AMP:ATP ratio and plays a central role in the regulation of energy homeostasis. Previously, AMPK was reported to phosphorylate serine 621 of Raf-1 in vitro. In the present study, we
Shin-ichiro Miura et al.
Biochemical and biophysical research communications, 306(4), 924-929 (2003-06-25)
Since we recently reported that high density lipoprotein, which contains the bioactive lipid sphingosine-1-phosphate (S1P) [Arterioscler. Thromb. Vasc. Biol. 23 (2003) 802], induced human coronary artery endothelial cell (HCEC) tube formation mediated by a Ras/Raf/ERK (extracellular signal-activated kinase) pathway, we
Michael R Bennett et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 23(18), 7207-7217 (2003-08-09)
Neurofibromatosis type 1 (NF1) patients are predisposed to learning disabilities, macrocephaly, and brain tumors as well as abnormalities on magnetic resonance imaging that are postulated to result from abnormal myelination. Here we show that Nf1+/- spinal cords in adult mice
Shin-Ichiro Miura et al.
Atherosclerosis, 175(2), 235-243 (2004-07-21)
Since we recently demonstrated that high-density lipoprotein induced human coronary artery endothelial cell (HCEC) tube formation through Ras/Raf/ERK (extracellular-signal-regulated kinase) activation [Arterioscler. Thromb. Vasc. Biol. 23 (2003) 802], it is possible that lipid-lowering agents such as statins, which reduce the
Shin Onodera et al.
The Journal of biological chemistry, 277(10), 7865-7874 (2001-12-26)
Neutral matrix metalloproteinases (MMPs) play an important role in bone matrix degradation accompanied by bone remodeling. We herein show for the first time that macrophage migration inhibitory factor (MIF) up-regulates MMP-13 (collagenase-3) mRNA of rat calvaria-derived osteoblasts. The mRNA up-regulation

문서

Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.

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