106425

N-Acetyl-L-cysteine

Mucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock.

• 동의어(들): N-Acetyl-L-cysteine, LNAC
• 실험식(Hill 표기법): C₅H₉NO₃S
• CAS Number: 616-91-1
• Molecular Weight: 163.19
• MDL number: MFCD00004880
• UNSPSC 코드: 12352209
• NACRES: NA.25

속성

• Quality Level: 200
• 분석: ≥98% (titration)
• 형태: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 색상: white
• solubility: water: 50 mg/mL
• 음이온 미량물: chloride (Cl^-): ≤0.04%; sulfate (SO₄^2-): ≤0.03%
• 양이온 미량물: Fe: ≤20 ppm
• 배송 상태: ambient
• 저장 온도: 15-25°C
• InChI: 1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)
• InChI key: PWKSKIMOESPYIA-UHFFFAOYSA-N

설명

일반 설명

A mucolytic agent and thio-based antioxidant. Increases the cellular pool of free-radical scavengers. Inhibits HIV replication. Prevents apoptotic death of neuronal cells. Antidote for acetaminophen poisoning. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.

Mucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock. Increases cellular pools of free-radical scavengers. Inhibitor of HIV replication. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.

애플리케이션

• Chlorpyrifos-induced suppression of the antioxidative defense system leads to cytotoxicity and genotoxicity in macrophages.: The study highlights the protective role of N-acetyl-L-cysteine against chlorpyrifos-induced oxidative damage in macrophages, emphasizing its importance in mitigating pesticide toxicity (Lu et al., 2024).


• N-Acetyl-L-Cysteine Attenuates Titanium Dioxide Nanoparticle (TiO2 NP)-Induced Autophagy in Male Germ Cells.: This research explores how N-acetyl-L-cysteine can mitigate the autophagic effects induced by titanium dioxide nanoparticles in male germ cells, suggesting its use in reproductive health (Shin et al., 2024).

포장

Packaged under inert gas

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.

기타 정보

Ortolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.
Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
Ferrari, G., et al. 1995. J. Neurosci.15, 2857.
Weinander, R., et al. 1994. J. Biol. Chem.269, 71.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable