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주요 문서

890895P

Avanti

18:1 TAP (DOTAP, MS Salt)

Avanti Research - A Croda Brand 890895P, powder

동의어(들):

1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt)

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크기 선택

25 MG
₩309,271
200 MG
₩642,292

₩309,271


예상 입고일2025년 2월 17일세부사항


벌크 견적 요청

크기 선택

보기 변경
25 MG
₩309,271
200 MG
₩642,292

About This Item

실험식(Hill 표기법):
C43H83NO8S
CAS Number:
Molecular Weight:
774.19
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25

₩309,271


예상 입고일2025년 2월 17일세부사항


벌크 견적 요청

양식

powder

포장

pkg of 2 × 100 mg (890895P-200mg)
pkg of 1 × 25 mg (890895P-25mg)

제조업체/상표

Avanti Research - A Croda Brand 890895P

지질 유형

cationic lipids
transfection

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.O=S([O-])(OC)=O

InChI

1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;

InChI key

RSMRWWHFJMENJH-LQDDAWAPSA-M

생화학적/생리학적 작용

1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) is a cationic lipid, used for in vitro and in vivo nucleic acid and protein delivery.[1] The lipid composition and cell type affects the transfection potential of DOTAP.[2] DOTAP mediates gene knockdown technique in hematopoietic stem cells (HSCs).[3]

포장

5 mL Clear Glass Sealed Ampule (890895P-200mg)
5 mL Clear Glass Sealed Ampule (890895P-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

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문서 라이브러리 방문

Dmitri Simberg et al.
Critical reviews in therapeutic drug carrier systems, 21(4), 257-317 (2005-01-11)
Cationic lipid-mediated nucleic acid and protein delivery is becoming increasingly popular for in vitro and in vivo applications. While the chemistry of cationic lipid carriers is moving very rapidly, and more and more sophisticated molecules are being developed, it is
Sabata Martino et al.
Journal of biomedicine & biotechnology, 2009, 410260-410260 (2009-06-09)
RNA interference technology is an ideal strategy to elucidate the mechanisms associated with human CD34(+) hematopoietic stem cell differentiation into dendritic cells. Simple manipulations in vitro can unequivocally yield alloreactive or tolerogenic populations, suggesting key implications of biochemical players that
Bieong-Kil Kim et al.
Biochimica et biophysica acta, 1848(10 Pt A), 1996-2001 (2015-06-27)
The effects of lipid compositions on their physicochemical properties and transfection efficiencies were investigated. Four liposome formulations with different 1,2-dioleoyl-3-trimethylammoniumpropane (DOTAP) to dioleoylphosphatidylethanolamine (DOPE) weight ratios were investigated, that is, weight ratios 1:0 (T1P0), 3:1 (T3P1), 1:1 (T1P1), and 1:3

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