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Merck
모든 사진(1)

문서

860829P

Avanti

18:0(2R-OH) Ceramide

Avanti Research - A Croda Brand 860829P, powder

동의어(들):

N-(2′-(R)-hydroxystearoyl)-D-erythro-sphingosine

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About This Item

실험식(Hill 표기법):
C36H71NO4
CAS Number:
Molecular Weight:
581.95
UNSPSC 코드:
12352211
NACRES:
NA.25

형태

powder

포장

pkg of 1 × 5 mg (860829P-5mg)

제조업체/상표

Avanti Research - A Croda Brand 860829P

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCCC)=O)CO

일반 설명

18:0(2R-OH) Ceramide is a unique ceramide containing 18C long chain base fatty acid (stearic acid)-with 2′-hydroxyl group in R configuration.

생화학적/생리학적 작용

18:0(2R-OH) Ceramide is essential for maintaining membrane fluidity.

포장

5 mL Amber Glass Screw Cap Vial (860829P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


시험 성적서(COA)

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문서 라이브러리 방문

Jennifer E Kyle et al.
The Analyst, 141(5), 1649-1659 (2016-01-07)
Understanding how biological molecules are generated, metabolized and eliminated in living systems is important for interpreting processes such as immune response and disease pathology. While genomic and proteomic studies have provided vast amounts of information over the last several decades
Lin Guo et al.
Journal of lipid research, 53(7), 1327-1335 (2012-04-21)
FA 2-hydroxylase (FA2H) is an NAD(P)H-dependent enzyme that initiates FA α oxidation and is also responsible for the biosynthesis of 2-hydroxy FA (2-OH FA)-containing sphingolipids in mammalian cells. The 2-OH FA is chiral due to the asymmetric carbon bearing the
Hiroko Hama
Biochimica et biophysica acta, 1801(4), 405-414 (2009-12-23)
2-Hydroxy fatty acids (hFA) are important components of a subset of mammalian sphingolipids. The presence of hFA in sphingolipids is best described in the nervous system, epidermis, and kidney. However, the literature also indicates that various hFA-sphingolipids are present in
Ana B Herrero et al.
Cancer research, 68(23), 9779-9787 (2008-12-03)
PM02734 is a novel synthetic antitumor drug that is currently in phase I clinical trials. To gain some insight into its mode of action, we used the yeast Saccharomyces cerevisiae as a model system. Treatment of S. cerevisiae with PM02734
Nathan L Alderson et al.
Journal of lipid research, 50(6), 1203-1208 (2009-01-28)
Sphingolipids are ubiquitous components of eukaryotic cells that regulate various cellular functions. In many cell types, a fraction of sphingolipids contain 2-hydroxy fatty acids, produced by fatty acid 2-hydroxylase (FA2H), as the N-acyl chain of ceramide [hydroxyl fatty acid (hFA)-sphingolipids].

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