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860536P

Avanti

Sphinganine-1-Phosphate (d18:0)

Avanti Research™ - A Croda Brand 860536P, powder

동의어(들):

D-erythro-sphinganine-1-phosphate

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크기 선택

1 MG
₩406,914

₩406,914

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모든 사진(1)

크기 선택

보기 변경
1 MG
₩406,914

About This Item

실험식(Hill 표기법):
C18H40NO5P
CAS Number:
19794-97-9
Molecular Weight:
381.49
MDL number:
MFCD00871363
UNSPSC 코드:
12352211
NACRES:
NA.25

₩406,914

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청

양식

powder

포장

pkg of 1 × 1 mg (860536P-1mg)
pkg of 1 × 5 mg (860536P-5mg)

제조업체/상표

Avanti Research™ - A Croda Brand 860536P

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@](CCCCCCCCCCCCCCC)(O)[C@]([NH3+])([H])COP([O-])(O)=O

InChI

1S/C18H40NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(20)17(19)16-24-25(21,22)23/h17-18,20H,2-16,19H2,1H3,(H2,21,22,23)/t17-,18+/m0/s1

InChI key

YHEDRJPUIRMZMP-ZWKOTPCHSA-N

일반 설명

Sphinganine-1-Phosphate (SA1P) is a bioactive lipid present in mammals. It is produced from the sphingoid base, sphinganine in the presence of sphingosine kinase (SPHK).[1]

애플리케이션

Sphinganine-1-Phosphate (d18:0) has been used as a reference standard in ultra performance liquid chromatography coupled to a mass spectrometry.[2] It is suitable for use as an internal standard for ultra high performance liquid chromatography for the quantification of blood and muscle sphingolipid.[1] Sphinganine-1-phosphate (d18:0) is also suitable for use as standard in liquid chromatography tandem mass spectrometry.[3]

생화학적/생리학적 작용

Sphinganine-1-Phosphate (SA1P) is an important marker for cancer and immune system disorders studies. It elicits protective functionality in hepatic ischemia.[3] Elevated levels of SA1P is observed in hepatocellular carcinoma.[4]

포장

5 mL Amber Glass Screw Cap Vial (860536P-1mg)
5 mL Amber Glass Screw Cap Vial (860536P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

또한 이 제품과 함께 일반적으로 구입

제품 번호
설명
가격

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Serum sphingolipidomic analyses reveal an upregulation of C16-ceramide and sphingosine-1-phosphate in hepatocellular carcinoma
Grammatikos G, et al.
Testing, 7(14), 18095-18095 (2016)
Accurate quantification of sphingosine-1-phosphate in normal and Fabry disease plasma, cells and tissues by LC-MS/MS with 13C-encoded natural S1P as internal standard
Mirzaian M, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 459(5), 36-44 (2016)
Exercise increases sphingoid base-1-phosphate levels in human blood and skeletal muscle in a time-and intensity-dependent manner
Baranowski M, et al.
European Journal of Applied Physiology, 115(5), 993-1003 (2015)
Metabolomic insights into system-wide coordination of vertebrate metamorphosis
Ichu T, et al.
BMC Developmental Biology, 14(1), 5-5 (2014)
Katja Jakobi et al.
International journal of molecular sciences, 21(7) (2020-04-05)
Hepatocellular carcinoma (HCC) shows a remarkable heterogeneity and is recognized as a chemoresistant tumor with dismal prognosis. In previous studies, we observed significant alterations in the serum sphingolipids of patients with HCC. This study aimed to investigate the in vitro

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