콘텐츠로 건너뛰기
Merck
모든 사진(2)

주요 문서

모든 문서 보기

850337P

Avanti

MAPCHO™-16

n-hexadecylphosphocholine, powder

동의어(들):

HPC; Fos-Choline-16; FOS16; FC-16; Miltefosine

로그인조직 및 계약 가격 보기

크기 선택

1 G
₩473,701
5 G
₩1,825,579

₩473,701

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청
모든 사진(2)

크기 선택

보기 변경
1 G
₩473,701
5 G
₩1,825,579

About This Item

실험식(Hill 표기법):
C21H46NO4P
CAS Number:
58066-85-6
Molecular Weight:
407.57
MDL number:
MFCD00133396
UNSPSC 코드:
12352211
NACRES:
NA.25

₩473,701

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청

분석

>99% (TLC)

양식

powder

포장

pkg of 1 × 1 g (850337P-1g)
pkg of 1 × 5 g (850337P-5g)

제조업체/상표

Avanti Research™ - A Croda Brand 850337P

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[P](=O)([O-])(OCC[N+](C)(C)C)OCCCCCCCCCCCCCCCC

InChI

1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3

InChI key

PQLXHQMOHUQAKB-UHFFFAOYSA-N

일반 설명

Hexadecylphosphocholine is a structural analog of palmitoyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid is often used as a detergent for membrane protein solubilization and purification. It has been shown to have antineoplastic and antiprotozoal activity.

애플리케이션

MAPCHO™-16 has been used to test against Leishmania intracellular amastigotes.[1] It has also been use to evaluate its efficacy in L. infantum chagasi infections.[2]

생화학적/생리학적 작용

MAPCHO™-16/ n-hexadecylphosphocholine/Miltefosine can be used as a stationary phase to determine total acidity of divalent cations by ion chromatography.[3] It is used in the oral treatment of human leishmaniasis [4]

포장

20 mL Clear Glass Screw Cap Vial (850337P-1g)
60 mL Amber Wide Mouth Glass Bottle with Screw Cap (850337P-5g)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC
MAPCHO is a trademark of Avanti Polar Lipids, LLC

픽토그램

Skull and crossbones
GHS06

신호어

Danger

유해 및 위험 성명서

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 문서 section.

도움이 필요하시면 연락하세요. 고객 지원 부서

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Combination therapy with nitazoxanide and amphotericin B, Glucantime, miltefosine and sitamaquine against Leishmania (Leishmania) infantum intracellular amastigotes
Mesquita JT, et al.
Acta Tropica, 130, 112-116 (2014)
Synthesis of 16-mercaptohexadecylphosphocholine, a miltefosine analog with leishmanicidal activity
Hornillos V, et al.
Bioorganic & medicinal chemistry letters, 16(19), 5190-5193 (2006)
Determination of total acidity and of divalent cations by ion chromatography with n-hexadecylphosphocholine as the stationary phase
Hu W, et al.
Journal of Chromatography A, 956(1-2), 139-145 (2002)
Juliana Q Reimão et al.
PLoS neglected tropical diseases, 9(2), e0003556-e0003556 (2015-02-14)
The only oral drug available for the treatment of leishmaniasis is miltefosine, described and approved for visceral leishmaniasis in India. Miltefosine is under evaluation for the treatment of cutaneous leishmaniasis in the Americas although its efficacy for the treatment of
Bruno M Castro et al.
The journal of physical chemistry. B, 117(26), 7929-7940 (2013-06-07)
Edelfosine (1-O-octadecyl-2-O-methyl-sn-glycero-phosphocholine) and miltefosine (hexadecylphosphocholine) are synthetic alkylphospholipids (ALPs) that are reported to selectively accumulate in tumor cell membranes, inducing Fas clustering and activation on lipid rafts, triggering apoptosis. However, the exact mechanism by which these lipids elicit these events

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.