810215P
Avanti
C12-NBD Phytosphingosine
N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-phytosphingosine, powder
동의어(들):
N-(NBD-Aminolauroyl)phytosphingosine
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모든 사진(1)
크기 선택
보기 변경
50 μG
₩198,636
About This Item
실험식(Hill 표기법):
C36H63N5O7
CAS Number:
Molecular Weight:
677.91
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25
추천 제품
분석
>99% (TLC)
양식
powder
포장
pkg of 1 × 50 μg (810215P-50ug)
제조업체/상표
Avanti Research™ - A Croda Brand 810215P
배송 상태
dry ice
저장 온도
−20°C
SMILES string
N[C@H]([C@H](O)[C@H](O)CCCCCCCCCCCCCC)CO
InChI
1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
InChI key
AERBNCYCJBRYDG-KSZLIROESA-N
일반 설명
C12-NBD Phytosphingosine is a fluorescent derivative of the naturally occurring lipid compound, phytosphingosine which is localised in skin, kidney and intestines.[1][2]
Phytosphingosine is a ceramide molecule localized to the stratum corneum.[3]
애플리케이션
C12-NBD Phytosphingosine has been used as a substrate in ceramidase activity assay to study enzyme activity.[4]
C12-NBD phytosphingosine has been used as a substrate to assay ceramidase activity.[4]
생화학적/생리학적 작용
In vitro studies using human epidermis model shows that melanin production is prevented by phytosphingosine. Hence, it is widely used in cosmetics.[5]
Phytosphingosine (PHS) is a sphingoid lipid molecule which is known to exhibit antimicrobial and anti-inflammatory action. PHS can has the ability to increase the production of keratinocyte differentiation marker proteins, such as transglutaminase 1 and involucrin, that are responsible for the development of cornifed envelope.[2] PHS metabolism results in the formation of glycerophospholipids, sphingolipids and even-numbered fatty acids which mainly include palmitic acid.[6]
포장
5 mL Amber Glass Screw Cap Vial (810215P-50ug)
법적 정보
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
가장 최신 버전 중 하나를 선택하세요:
Anti-melanogenic activity of phytosphingosine via the modulation of the microphthalmia-associated transcription factor signaling pathway
Jang EL, et al.
Journal of Dermatological Science, 87(1), 19-28 (2017)
Phytosphingosine and sphingosine ceramide headgroup hydrogen bonding: structural insights through thermotropic hydrogen/deuterium exchange
Rerek ME, et al.
The Journal of Physical Chemistry B, 105(38), 9355-9362 (2001)
Fluorescent and Luminescent Probes for Biological Activity (1999)
Hyun Kyung Choi et al.
Archives of dermatological research, 309(10), 795-803 (2017-09-25)
Phytosphingosine (PHS) is a sphingoid that is a key component of phytoceramides NP, AP and EOP. PHS has been known to have anti-inflammation and antimicrobial activities and to stimulate epidermal differentiation. In addition, it is reported that PHS treatment notably
Li-Yu Chen et al.
Nature communications, 6, 6030-6030 (2015-01-17)
Turgor pressure plays pivotal roles in the growth and movement of walled cells that make up plants and fungi. However, the molecular mechanisms regulating turgor pressure and the coordination between turgor pressure and cell wall remodelling for cell growth remain
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