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130672

Sigma-Aldrich

N-Hydroxysuccinimide

N-Hydroxysuccinimide

98%

동의어(들):

1-Hydroxy-2,5-pyrrolidinedione, HOSu, NHS

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크기 선택

5 G
₩45,675
25 G
₩120,176
100 G
₩308,256
250 G
₩689,490
1 KG
₩1,131,522
5 KG
₩3,554,429

₩45,675

출고 가능일2025년 4월 23일세부사항

벌크 견적 요청
모든 사진(5)

크기 선택

보기 변경
5 G
₩45,675
25 G
₩120,176
100 G
₩308,256
250 G
₩689,490
1 KG
₩1,131,522
5 KG
₩3,554,429

About This Item

실험식(Hill 표기법):
C4H5NO3
CAS Number:
6066-82-6
Molecular Weight:
115.09
Beilstein:
113913
EC Number:
228-001-3
MDL number:
MFCD00005516
UNSPSC 코드:
12352115
PubChem Substance ID:
24847975
NACRES:
NA.22

₩45,675

출고 가능일2025년 4월 23일세부사항

벌크 견적 요청

Quality Level

200

분석

98%

양식

solid

mp

95-98 °C (lit.)

작용기

imide

SMILES string

ON1C(=O)CCC1=O

InChI

1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2

InChI key

NQTADLQHYWFPDB-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

N-Hydroxysuccinimide can be used in the synthesis of N-hydroxysuccinimide ester via dehydration reaction in the presence of dicyclohexylcarbodiimide in carboxylic acid.[1]
N-Hydroxysuccinimide has been used in the synthesis of intermediates such as:
  • N

  • -succinimidyl 3-(di-tert-butylfluorosilyl)benzoate[2]
  • 4-[2,2-bis[(p-tolylsulfonyl)-methyl] acetyl]benzoic acid-NHS ester[3]
  • N-succinimidyl 3-iodobenzoate[4]

It has also been used in a protocol for the surface modification of microchannels of a microfluidic-integrated surface plasmon resonance (SPR) platform for the detection and quantification of bacterial pathogens.[5]
Additive used in the carbodiimide method for improved amidations[6] and peptide couplings.[7]

픽토그램

Corrosion
GHS05

신호어

Danger

유해 및 위험 성명서

H315,H318

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
WXBF5431V
0000428358
0000428358
MKCX2952
MKCX2951

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Polycyclic Aromat. Compd., 3, 781-781 (1993)
PEGylation of native disulfide bonds in proteins.
Brocchini S
Nature Protocols, 1(5), 2241-2241 (2006)
Pico Y et al.
Food Toxicants Analysis: Techniques, Strategies and Developments (2007)
Zbigniew Czajgucki et al.
Journal of peptide science : an official publication of the European Peptide Society, 12(10), 653-662 (2006-07-19)
Edeines are pentapeptide amide antibiotics composed of four nonprotein amino acids, glycine, and polyamine. They exhibit antimicrobial and immunosuppressive activities and are universal inhibitors of translation. Moreover, it was proven that the free ionizable carboxy group in the (2R, 6S
Preparation of N-succinimidyl 3-[* I] iodobenzoate: an agent for the indirect radioiodination of proteins.
Vaidyanathan G
Nature Protocols, 1(2), 707-707 (2006)
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질문

1–10 / 10 질문  

  1. is there any reported data for cell's toxicity for this compound?

    1 답변

    1. Unfortunately, cell toxicity is not a specification tested for this product.

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 답변

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 답변

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  4. What is the storage temperature of NHS? (Product number: 130672)

    1 답변

    1. This product is stored at room temperature.

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  5. Hello, Could you tell me the percentage of impurities and define specifically which impurities we can find in this reagent ? Thank you,

    1 답변

    1. The impurities of this product are not identified or quantified.
      Please view the Specification Sheet to see the specified tests: https://www.sigmaaldrich.com/specification-sheets/190/101/130672-BULK_______ALDRICH__.pdf.

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  6. Does N-Hydroxysuccinimide WATER SOLUBLE?

    1 답변

    1. Yes, this product is water soluble at 50mg/ml

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  7. What is the purity of Product 130672, N-Hydroxysuccinimide?

    1 답변

    1. The purity is lot specific and will be stated on the Specification Sheet.

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  8. Does N-Hydroxysuccinimide go by any other names?

    1 답변

    1. Yes, N-Hydroxysuccinimide is also referred to by the acronym NHS and is also referred to by the synonyms 1-Hydroxy-2,5-pyrrolidinedione and HOSu.

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  9. What is the solution stability of Product 130672, N-Hydroxysuccinimide?

    1 답변

    1. Sigma-Aldrich does not evaluate 130672 for solution stability. Therefore, it is advisable to prepare a solution fresh for each use. Please note, the product is moisture sensitive.

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  10. What is the Department of Transportation shipping information for this product?

    1 답변

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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활성 필터

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