L021000

DCA Deblock

with Dichloromethane

• UNSPSC 코드: 41116004
• NACRES: NA.21

속성

• 유형: for DNA synthesis; for DNA synthesis
• 제품 라인: Proligo Reagents
• 양식: liquid
• 저장 조건: dry at room temperature
• 농도: 42.2-51.6 g/L (DCA content, titration)
• 불순물: ≤200 ppm water content (Karl Fischer)
• 색상: clear

설명

일반 설명

Deblock solution contains dichloroacetic acid (DCA) in dichloromethane that assists in the removal of the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, before the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.

제조 메모

Dicloromethane / Dichloroacetic acid 97/3 (v/v)

기타 정보

Deblock solution containing dichloroacetic acid (DCA) in dichloromethane removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.

안전성 정보

• 픽토그램: GHS08,GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H315,H318,H336,H351,H360FD,H362
• 예방조치 성명서: P202 - P263 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Dam. 1 - Lact. - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Central nervous system
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable