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Merck
모든 사진(1)

주요 문서

860646

Sigma-Aldrich

1-Methyl-DL-tryptophan

97%

동의어(들):

1-Methyl-DL-tryptophan, 1-Methyltryptophan, 2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, 2-Amino-3-(1-methyl-1H-indol-3-yl)propanoicacid, 2-Amino-3-(1-methylindol-3-yl)propanoic acid, DL-1-Methyltryptophan, N′-Methyl-DL-tryptophan

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크기 선택

250 MG
₩310,692
1 G
₩488,824

₩310,692


출고 가능일2025년 4월 21일세부사항


벌크 견적 요청

크기 선택

보기 변경
250 MG
₩310,692
1 G
₩488,824

About This Item

실험식(Hill 표기법):
C12H14N2O2
CAS Number:
Molecular Weight:
218.25
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

₩310,692


출고 가능일2025년 4월 21일세부사항


벌크 견적 요청

Quality Level

분석

97%

양식

solid

mp

250 °C (dec.) (lit.)

작용기

amine
carboxylic acid

SMILES string

Cn1cc(CC(N)C(O)=O)c2ccccc12

InChI

1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)

InChI key

ZADWXFSZEAPBJS-UHFFFAOYSA-N

애플리케이션

1-Methyl-DL-tryptophan, a competitive inhibitor of indoleamine 2,3 dioxygenase-1 (IDO1), has been used to study inflammation-induced depression in mice[1] and syncytial virus induced bronchiolitis.[2]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Motivational changes that develop in a mouse model of inflammation-induced depression are independent of indoleamine 2, 3 dioxygenase.
Vichaya, Elisabeth G et al.
Neuropsychopharmacology (2018)
Seung-Ha Yang et al.
Experimental & molecular medicine, 41(5), 315-324 (2009-03-25)
Mesenchymal stem cells (MSCs) can inhibit T cell proliferation; however, the underlying mechanisms are not clear. In this study, we investigated the mechanisms of the immunoregulatory activity of MSCs on T cells. Irradiated MSCs co-cultured with either na?ve or pre-activated
Qi-Xiang Ye et al.
Experimental and therapeutic medicine, 14(3), 1884-1891 (2017-10-01)
Cytotoxic T-lymphocyte-associated protein 4 immunoglobulin (CTLA4Ig) and anti-cluster of differentiation 154 (anti-CD154) are able to block B7/CD28 and CD40/CD154 co-stimulatory signals in T cells. Additionally, they promote hematopoietic stem cell transplantation (HSCT) in sensitized recipients and are able to induce
Gavin Carr et al.
Journal of medicinal chemistry, 51(9), 2634-2637 (2008-04-09)
Synthetic analogues of the sponge natural product exiguamine A (3) have been prepared and evaluated for their ability to inhibit indoleamine 2,3-dioxygenase in vitro.
Neda Milosavljevic et al.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 23(8), 1040-1050 (2017-05-10)
Mesenchymal stem cells (MSCs) are, due to immunomodulatory characteristics, considered as novel agents in the treatment of immune-mediated acute liver failure. Although it is known that MSCs can regulate activation of T lymphocytes, their capacity to modulate function of neutrophils

질문

  1. What is the recommended storage temperature and solubility of this product no.860646, 1-Methyl-DL-tryptophan?

    1 답변
    1. This product may be stored at room temperature. The solubility of this product has not been determined. However, according to the literature, this compound is soluble in methanol and acetic acid (2 %) at approximately 0.1 mg/mL and 1 mg/mL, respectively.

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