콘텐츠로 건너뛰기
Merck
모든 사진(3)

주요 문서

452483

Sigma-Aldrich

1-Methyl-D-tryptophan

95%, for peptide synthesis

동의어(들):

(2R)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, D-(+)-1-Methyltryptophan

로그인조직 및 계약 가격 보기

크기 선택

250 MG
₩100,282
1 G
₩185,339
10 G
₩890,663

₩100,282


출고 가능일2025년 4월 23일세부사항


벌크 견적 요청

크기 선택

보기 변경
250 MG
₩100,282
1 G
₩185,339
10 G
₩890,663

About This Item

실험식(Hill 표기법):
C12H14N2O2
CAS Number:
Molecular Weight:
218.25
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.22

₩100,282


출고 가능일2025년 4월 23일세부사항


벌크 견적 요청

제품명

1-Methyl-D-tryptophan, 95%

Quality Level

분석

95%

양식

lumps and powder

광학 활성

[α]22/D +12.4°, c = 2 in acetic acid

반응 적합성

reaction type: solution phase peptide synthesis

mp

242-245 °C (lit.)

응용 분야

peptide synthesis

SMILES string

Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12

InChI

1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m1/s1

InChI key

ZADWXFSZEAPBJS-SNVBAGLBSA-N

애플리케이션

Used to prepare a number of natural products including macroline alkaloids using the Pictet-Spengler reaction of tryptophan esters with aldehydes[1] also used in the synthesis of 1-substituted indolactam precursors.[2]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Zhidan Tu et al.
Stem cells and development, 19(11), 1803-1809 (2010-02-19)
Mesenchymal stem cells (MSCs) possess potent and broad immunosuppressive capabilities, and have shown promise in clinical trials treating many inflammatory diseases. Previous studies have found that MSCs inhibit dendritic cell, T-cell, and B-cell activities in the adaptive immunity; however, whether
Franco Carranza et al.
PloS one, 7(7), e40356-e40356 (2012-08-01)
Dendritic cells (DC) have the potential to control the outcome of autoimmunity by modulating the immune response. In this study, we tested the ability of Fasciola hepatica total extract (TE) to induce tolerogenic properties in CpG-ODN (CpG) maturated DC, to
Cook, J.M. et al.
Heterocycles, 27, 2795-2795 (1988)
Irie, K. et al.
Tetrahedron, 51, 6255-6255 (1995)
Shoba Amarnath et al.
PLoS biology, 8(2), e1000302-e1000302 (2010-02-04)
Immunotherapy using regulatory T cells (Treg) has been proposed, yet cellular and molecular mechanisms of human Tregs remain incompletely characterized. Here, we demonstrate that human Tregs promote the generation of myeloid dendritic cells (DC) with reduced capacity to stimulate effector

질문

1–5 / 5 질문  
  1. I have a question regarding 1-methyl-D-tryptophan (452483). Is this suitable for cell culture study purpose? Thank you.

    1 답변
    1. This product is listed as suitable for peptide synthesis. It may be okay for cell culture, but it is not tested with that application in mind, so the suitability would need to be determined by the end user. What is tested can be found on the product COA, an example of which can be found in the 'Documentation' section of the product page.

      도움이 되었습니까?

  2. What is Product 452483, 1-Methyl-D-tryptophan, soluble in?

    1 답변
    1. While we don't test the solubility of this product directly, we do have to dissolve it in acetic acid in order to test the optical rotation. We would also expect this to be soluble in a dilute hydrochloric acid solution (50mg/mL in 5N HCl). Both heat and sonication may be required in order to prepare a homogenous solution. Also, based on our experience with the DL (Product No. 860646) and L (Product No. 447439) forms, we would expect that dilute sodium hydroxide would also be a potential solvent (1g/100mL of 1M NaOH).

      도움이 되었습니까?

  3. What is the solution stability of Product 452483, 1-Methyl-D-tryptophan?

    1 답변
    1. Unfortunately, we do not perform solution stability testing on this item or have experience with storing tryptophan solutions, so we would recommend making a fresh batch with each use.

      도움이 되었습니까?

  4. What is the Department of Transportation shipping information for this product?

    1 답변
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      도움이 되었습니까?

  5. How should Product 452483, 1-Methyl-D-tryptophan, be stored?

    1 답변
    1. This material is stable at room temperature without any special handling precautions.

      도움이 되었습니까?

후기

평점 값 없음

활성 필터

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.