Poly(vinyl pyrrolidone) is commonly used in biomedical applications. The end group functionality contains a cyanomethyl group; and the RAFT agent diphenylcarbamodithioate which will allow for additional polymerization to generate a diblock copolymer. This RAFT agent is well-suited for vinyl acetates and vinyl benzoate monomers.
Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.
Microparticles in drug delivery: Study on controlling chitosan microparticle size and distribution, exploring encapsulation of BSA and TPP cross-linker.
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