654280
1-(Phenylsulfonyl)-3-indolylboronic acid pinacol ester
97%
동의어(들):
1-(Phenylsulfonyl)-3-indoleboronic acid pinacol ester
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모든 사진(1)
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1 G
₩102,414
5 G
₩438,785
About This Item
실험식(Hill 표기법):
C20H22BNO4S
CAS Number:
Molecular Weight:
383.27
MDL number:
UNSPSC 코드:
12352103
PubChem Substance ID:
NACRES:
NA.22
추천 제품
Quality Level
분석
97%
양식
solid
mp
120-125 °C
SMILES string
CC1(C)OB(OC1(C)C)c2cn(c3ccccc23)S(=O)(=O)c4ccccc4
InChI
1S/C20H22BNO4S/c1-19(2)20(3,4)26-21(25-19)17-14-22(18-13-9-8-12-16(17)18)27(23,24)15-10-6-5-7-11-15/h5-14H,1-4H3
InChI key
OMZLHWZHHPAZPW-UHFFFAOYSA-N
애플리케이션
1-(Phenylsulfonyl)-3-indolylboronic acid pinacol ester can be used:
- In one or two key synthetic steps for the preparation of a key intermediate of lycogarubin C.[1]
- To prepare 3-(4,5-dibromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-2-yl)-1-(phenylsulfonyl)-1H-indole, a key intermediate for the synthesis of tubulin inhibitor VERU-111 analogs.[2]
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Qinghui Wang et al.
Journal of medicinal chemistry, 61(17), 7877-7891 (2018-08-21)
Colchicine binding site inhibitors (CBSIs) hold great potential in developing new generations of antimitotic drugs. Unlike existing tubulin inhibitors such as paclitaxel, they are generally much less susceptible to resistance caused by the overexpression of drug efflux pumps. The 3,4,5-trimethoxyphenyl
John T Gupton et al.
Tetrahedron, 70(52), 9759-9767 (2015-01-15)
Lycogarubin C, permethyl storniamide A and lamellarin G trimethyl ether are pyrrole containing, natural products, which exhibit interesting biological properties. Such properties include anti-tumor activity on a variety of cancer cell lines including those that confer drug resistance, inhibition of
활성 필터
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
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