407852

tert-Butyldimethylsilyl cyanide

97%

• 동의어(들): tert-Butyl-cyano-dimethylsilane
• Linear Formula: (CH₃)₃CSi(CH₃)₂CN
• CAS Number: 56522-24-8
• Molecular Weight: 141.29
• Beilstein: 2234709
• MDL number: MFCD00054923
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24865490
• NACRES: NA.22

속성

• 분석: 97%
• mp: 76-79 °C (lit.)
• SMILES string: CC(C)(C)[Si](C)(C)C#N
• InChI: 1S/C7H15NSi/c1-7(2,3)9(4,5)6-8/h1-5H3
• InChI key: CWAKIXKDPQTVTA-UHFFFAOYSA-N

설명

일반 설명

tert-Butyldimethylsilyl cyanide (TBDMSCN) is a bulkier trialkylsilylcyanide.[1] It participates in the cyanosilylation of enantiopure 4-oxoazetidine-2-carbaldehydes.[2] Addition of TBDMSCN to sterically hindered ketones in the presence of Lewis acid or base catalyst has been studied. ZnI₂-catalyzed addition of TBDSCN to 2,2-dimethylcyclohexanone, 2,2,6-trimethylcyclohexanone and 2,2,6,6-tetramethylcyclohexanone affords protected cyanohydrins.[3]

애플리케이션

tert-Butyldimethylsilyl cyanide may be used as reagent for the formation of β-isonitrile alcohols via epoxides.[4]

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301 + H311 + H331
• 예방조치 성명서: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges