325090

Methyl (R)-(+)-3-bromo-2-methylpropionate

97%

• 동의어(들): (+)-Methyl (R)-β-bromoisobutyrate
• Linear Formula: BrCH₂CH(CH₃)CO₂CH₃
• CAS Number: 110556-33-7
• Molecular Weight: 181.03
• Beilstein: 1720833
• MDL number: MFCD00010639
• UNSPSC 코드: 12352101
• PubChem Substance ID: 24859486
• NACRES: NA.22

속성

• 분석: 97%
• 형태: liquid
• 광학 활성: [α]20/D +16°, neat
• 광학 순도: ee: 99% (GLC)
• refractive index: n20/D 1.455 (lit.)
• bp: 85 °C/37 mmHg (lit.)
• density: 1.422 g/mL at 25 °C (lit.)
• 작용기: bromo; ester
• SMILES string: COC(=O)[C@@H](C)CBr
• InChI: 1S/C5H9BrO2/c1-4(3-6)5(7)8-2/h4H,3H2,1-2H3/t4-/m0/s1
• InChI key: FKWNAVCXZSQYTA-BYPYZUCNSA-N

설명

애플리케이션

Methyl (R)-(+)-3-bromo-2-methylpropionate can be used as a reactant to prepare:

• (S)-3-(6-Methoxy-pyridin-3-yl)-2-methylpropionic acid methylester by reacting with 5-bromo-2-methoxy pyridine via nucleophilic displacement reaction.
• Decahydroisoquinoline derivative (NVP-ACQ090) as a potent antagonist of somatostatin sst3 receptor.

It can also be used as a reference compound in the enantioselective alkylation reaction of hydrophobic vitamin B12 derivatives.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): 163.4 °F - closed cup
• Flash Point (°C): 73 °C - closed cup
• 개인 보호 장비: Eyeshields, Gloves, type ABEK (EN14387) respirator filter