79625

N,N-Dimethylphosphoramic dichloride

≥98.0% (AT)

• 동의어(들): DMPADC, Dimethylamidophosphoric dichloride
• Linear Formula: (CH₃)₂NP(O)Cl₂
• CAS Number: 677-43-0
• Molecular Weight: 161.95
• Beilstein: 969956
• EC Number: 211-641-2
• MDL number: MFCD00013896
• UNSPSC 코드: 12352100
• PubChem Substance ID: 57652812
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥98.0% (AT)
• 양식: liquid
• refractive index: n20/D 1.464
• bp: 77-79 °C/11 mmHg (lit.)
• density: 1.362 g/mL at 20 °C (lit.)
• 작용기: phosphoramide
• 저장 온도: 2-8°C
• SMILES string: CN(C)P(Cl)(Cl)=O
• InChI: 1S/C2H6Cl2NOP/c1-5(2)7(3,4)6/h1-2H3
• InChI key: YNHXBEVSSILHPI-UHFFFAOYSA-N

설명

애플리케이션

N,N-Dimethylphosphoramic dichloride can be used as a reagent:

• For the activation of carboxylic acids.[1][2]
• To prepare functionalized β-lactams by reacting with acetic acids and imines.[2]
• To synthesize phosphoramidic esters by reacting with alcohols in the presence of a base catalyst.[3]
• To prepare [1,2,4]triazolo[4,3-c][1,3,5,2]triazaphosphinine-5-oxide derivatives by reacting with N-alkyl/aryl-N′-(4H-1,2,4-triazol-3-yl) amidines in the presence of triethylamine.[4]

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H314
• 예방조치 성명서: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter