1659000

チメロサール

United States Pharmacopeia (USP) Reference Standard

• 別名: 2-(エチルメルクリオメルカプト)安息香酸 ナトリウム塩, エチルメルクリチオサリチル酸 ナトリウム塩, エチルメルクリチオサリチル酸ナトリウム, 水銀-([o-カルボキシフェニル]チオ)エチル ナトリウム塩
• 化学式: 2-(C₂H₅HgS)C₆H₄CO₂Na
• CAS番号: 54-64-8
• 分子量: 404.81
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329751274
• MDL number: MFCD00013062
• Beilstein/REAXYS Number: 8169555

特性

• grade: pharmaceutical primary standard
• agency: USP
• API family: thimerosal
• manufacturer/tradename: USP
• mp: 234-237 °C (dec.) (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: [Na+].CC[Hg]Sc1ccccc1C([O-])=O
• InChI: 1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
• InChI key: RTKIYNMVFMVABJ-UHFFFAOYSA-L

詳細

General description

Find answers to frequently asked questions on USP products in USP FAQs.

この製品は薬局方標準品です。発行元の薬局方により製造・供給されています。詳しい情報は、発行元の薬局方のウェブサイトよりご確認ください。

Application

Thimerosal USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Thimerosal Tincture
• Thimerosal Topical Aerosol^®
• Thimerosal Topical Solution

Biochem/physiol Actions

チメロサールは、PI3-キナーゼ-依存型メチオニンシンターゼ、グルタミン酸輸送受容体、またNa⁺+K⁺依存型ATPアーゼのような、広い範囲のスルフヒドリル-依存型酵素やタンパク質を阻害できるスルフヒドリル(チオール)酸化剤です。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Legal Information

Aerosol is a registered trademark of Cytec Technology Corp.

Disclaimer

As part of the corporationglobal plan to support the Minamata Convention in eliminatingmercury-containing compounds, as of January 2021 customers will be required toprovide an End-Use Declaration. The sales of thimerosal will be restricted forapproved applications only, such as preservative in vaccine manufacturing,preservative in eye cosmetics, research use within academia (excludingpreservation intent) and as reference material only. The product is notintended for use as a biocide under global biocide regulations, including butnot limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act ,European Biocidal Products Regulation, Canada’s Pest Management RegulatoryAgency, Turkey’s Biocidal Products Regulation,Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR)and others.

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

安全性情報

• pictograms: GHS06,GHS08,GHS09
• signalword: Danger
• hcodes: H300 + H310 + H330,H373,H410
• pcodes: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral
• target_organs: Kidney
• 保管分類: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable