569251-U

Discovery^® HS C18 (3 µm) HPLC Columns

L × I.D. 7.5 cm × 4.6 mm, HPLC Column

• 別名: Discovery RP18 HPLC Column
• UNSPSCコード: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

特性

• product name: Discovery^® HS C18 HPLCカラム, 3 μm particle size, L × I.D. 7.5 cm × 4.6 mm
• 物質: stainless steel column
• 認証: suitable for USP L1
• 製品種目: Discovery^®
• 特徴: endcapped
• メーカー／製品名: Discovery^®
• 包装: 1 ea of
• 標識化の程度: 20% Carbon loading
• パラメーター: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• テクニック: HPLC: suitable; LC/MS: suitable
• L × 内径: 7.5 cm × 4.6 mm
• 表面積: 300 m²/g
• 表面被覆率: 3.2 μmol/m²
• 不純物: <10 ppm metals
• マトリックス: silica gel, high purity, spherical particle platform; fully porous particle
• マトリックス活性基: C18 (octadecyl) phase
• 粒径: 3 μm
• ポアサイズ: 120 Å
• operating pH range: 2-8
• アプリケーション: food and beverages
• 分離法: reversed phase

詳細

詳細

Discovery^® HS C18 HPLC column (L × I.D. 7.5 cm × 4.6 mm) is generally found to be stable under acidic and basic conditions.

アプリケーション

• A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies.: This research demonstrates the use of the Discovery^® HS C18 HPLC Column in developing a robust HPLC method for analyzing molnupiravir, showcasing its importance in current pandemic-related pharmaceutical research (Recber et al., 2022).


• A new RP-HPLC method as an auxiliary tool for optimization of sample preparation procedures for tracing of PPCPs of different hydrophilicities.: Highlights the adaptability of the Discovery^® HS C18 HPLC Column in environmental monitoring, specifically for pharmaceutical and personal care products, enhancing analytical methods for environmental safety (Portillo-Castillo et al., 2021).


• Analysis of terizidone in plasma using HPLC-UV method and its application in a pharmacokinetic study of patients with drug-resistant tuberculosis.: This study uses the Discovery^® HS C18 HPLC Column to assess terizidone levels in patient plasma, providing critical insights into the treatment of drug-resistant tuberculosis (Mulubwa and Mugabo, 2018).


• Optimization of LC method for the quantification of doxorubicin in plasma and urine samples in view of pharmacokinetic, biomedical and drug monitoring therapy studies.: Depicts the utility of the Discovery^® HS C18 HPLC Column in optimizing liquid chromatography methods for the potent chemotherapeutic agent doxorubicin, underscoring its role in therapeutic drug monitoring (Maliszewska et al., 2018).


• Universal efavirenz determination in transport study, rat placenta perfusion and placenta lysate by HPLC-UV.: Showcases the Discovery^® HS C18 HPLC Column′s application in studying the permeability and transport of efavirenz across the placenta, providing valuable pharmacological insights (Zelena et al., 2017).

特徴および利点

• 安定で、低ブリ-ドのLC-MS分離
• 分析から分取まで適応可能
• 安定性が高く、操作間、ロット間の再現性を保証
• 疎水性が高く、難しい分析対象物の高い分離能

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法的情報

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable