T2528

テルブタリン ヘミ硫酸塩

• 別名: 2-t-ブチルアミノ-1-(3,5-ジヒドロキシフェニル)エタノール
• 化学式: C₁₂H₁₉NO₃ · 1/2H₂SO₄
• CAS番号: 23031-32-5
• 分子量: 274.32
• EC Number: 245-386-3
• MDL番号: MFCD00079584
• UNSPSCコード: 12352200
• PubChem Substance ID: 24278729
• NACRES: NA.77

特性

• 溶解性: H₂O: soluble 100 mg/mL, clear to slightly hazy, colorless to yellow
• オーガナイザー: Novartis
• SMILES記法: OS(O)(=O)=O.CC(C)(C)NCC(O)c1cc(O)cc(O)c1.CC(C)(C)NCC(O)c2cc(O)cc(O)c2
• InChI: 1S/2C12H19NO3.H2O4S/c2*1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8;1-5(2,3)4/h2*4-6,11,13-16H,7H2,1-3H3;(H2,1,2,3,4)
• InChI Key: KFVSLSTULZVNPG-UHFFFAOYSA-N
• 遺伝子情報: human ... ADRB1(153) , ADRB2(154) , ADRB3(155)

詳細

アプリケーション

Terbutaline hemisulfate has been used as a reference standard for the determination of β agonist residues in meat⁴. It has also been used as a standard for developing LC-MS-MS based techniques for the analysis of veterinary drugs⁵.

生物化学的／生理学的作用

Terbutaline is a β-adrenoceptor agonist and is known to function as a bronchodilator. Studies have reported that terbutaline is potent inhibitor of premature labor⁶.

特徴および利点

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調製ノート

Terbutaline hemisulfate salt dissolves in water at 100 mg/ml to yield a colorless to yellow, clear to slightly hazy solution.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H361,H370
• 注意書き: P202 - P260 - P264 - P270 - P280 - P308 + P311
• 危険有害性の分類: Repr. 2 - STOT SE 1
• ターゲットの組織: Cardio-vascular system
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges