SRP8049
Periostin mouse
recombinant, expressed in CHO cells, FLAG® tagged, >95% (SDS-PAGE)
別名:
OSF-2, Osteoblast-specific factor 2, PC cell-derived growth factor
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10 μG
￥54,060
￥54,060
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10 μG
￥54,060
About This Item
UNSPSCコード:
12352200
NACRES:
NA.32
￥54,060
Check Cart for Availability
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由来生物
mouse
リコンビナント
expressed in CHO cells
タグ
FLAG® tagged
アッセイ
>95% (SDS-PAGE)
フォーム
lyophilized
分子量
~85 kDa
包装
pkg of 10 μg
保管条件
avoid repeated freeze/thaw cycles
不純物
<0.1 EU/μg endotoxin, tested
色
white
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
遺伝子情報
mouse ... Postn(50706)
詳細
Periostin (POSTN) is also called as osteoblast-specific factor 2.[1] It is a matricellular protein,[1] located in the alveolar walls.[1] This gene is located on human chromosome 13q13.[2]
Periostin was originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein (BMP-2). Abnormal expression of periostin is also linked to angiogenesis and metastasis in epithelial tumors.
生物化学的／生理学的作用
Periostin (POSTN) participates in collagen fibrillogenesis.[1] It plays a major role in the development of scar after traumatic spinal cord injury (SCI).[3] Periostin controls the activities of fibrocyte to stimulate myofibroblast differentiation and lung fibrosis.[1] It modulates the amount of collagen in tissue. Periostin also participates in the assembly of the extracellular matrix (ECM) architecture.[4]
物理的形状
凍結乾燥品(PBS)。
再構成
Reconstitute with 100 μL deionized water.
その他情報
Mouse periostin (aa 24-783) (isoform 5) is fused at the C-terminus to a FLAG®-tag.
法的情報
FLAG is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類コード
10 - Combustible liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SRP8049-10UG:
最新バージョンのいずれかを選択してください：
Shoichiro Ohta et al.
PloS one, 12(3), e0174547-e0174547 (2017-03-30)
The natural course of idiopathic pulmonary fibrosis (IPF) is variable. Predicting disease progression and survival in IPF is important for treatment. We previously demonstrated that serum periostin has the potential to be a prognostic biomarker for IPF. Our aim was
Teresa Cobo et al.
PloS one, 11(1), e0147837-e0147837 (2016-01-26)
Periostin is an extracellular matrix protein highly expressed in collagen-rich tissues subjected to continuous mechanical stress. Functionally, periostin is involved in tissue remodeling and its altered function is associated to numerous pathological processes. In orthodontics, periostin plays key roles in
Jin Ho Hwang et al.
American journal of nephrology, 46(6), 501-517 (2017-12-22)
Periostin is responsible for tissue regeneration, fibrosis, and wound healing via its interaction with integrin. Recently, the role of periostin has been shown to contribute to fibrosis in chronic kidney disease. We investigated the role of periostin and the effect
A K Devrim et al.
Bratislavske lekarske listy, 118(11), 705-709 (2017-12-09)
Although the molecular mechanism of cardiac healing is not fully understood, myocardial infarction is one of the most usual diagnoses in hospitalized patients in industrialized nations while periostin has been recently suggested to have a potential in tissue repairing following
Periostin regulates fibrocyte function to promote myofibroblast differentiation and lung fibrosis.
Ashley SL, et al.
Mucosal Immunology, 10(2), 341?351-341?351 (2017)
アクティブなフィルタ
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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