Human dpy-30 homolog, or DPY30 (GenBank Accession No. NM_032574) amino acids 2 – 99 (end) with N-terminal His-tag, MW= 12 kDa, expressed in an E. coli expression system.
The Journal of cell biology, 186(3), 343-353 (2009-08-05)
Histone lysine methyltransferase complexes are essential for chromatin organization and gene regulation. Whether any of this machinery functions in membrane traffic is unknown. In this study, we report that mammal Dpy-30 (mDpy-30), a subunit of several histone H3 lysine 4
The Journal of biological chemistry, 284(36), 24242-24256 (2009-06-27)
Transcription in eukaryotic genomes depends on enzymes that regulate the degree of histone H3 lysine 4 (H3K4) methylation. The mixed lineage leukemia protein-1 (MLL1) is a member of the SET1 family of H3K4 methyltransferases and is frequently rearranged in acute