おすすめの製品
品質水準
アッセイ
≥98% (HPLC)
形状
powder
保管条件
protect from light
色
white to beige
溶解性
DMSO: 2 mg/mL, clear
保管温度
-10 to -25°C
生物化学的／生理学的作用
Antioxidant, anti-cancer flavanonol with anti-alcohol intoxication effects, significantly impacts metabolic regulation and cancer chemoprevention through pathways like AMPK and SPHK1/mTOR.Dihydromyricetin (DHM) is a potent flavonoid known for its antioxidative, anti-inflammatory, anticancer, and antimicrobial properties, and plays a key role in modulating metabolism with minimal side effects. It operates by either scavenging or generating reactive oxygen species (ROS) to selectively target cancer cells, while sparing normal cells. DHM acts through multiple pathways including AMPK, affecting autophagy and glucose transport. Additionally, Dihydromyricetin inhibits ferroptosis via the SPHK1/mTOR pathway, modulates the Prx2 cascade through Nrf2, and contributes to cancer prevention and diabetes treatment by altering redox balance, gene expression, and improving metabolism, also involving AMPK, PI3K/Akt, PPAR pathways, and microRNAs.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SML4070-VAR:
SML4070-5MG:
SML4070-25MG:
SML4070-BULK:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Jie Fang et al.
Clinical and experimental pharmacology & physiology, 51(3), e13833-e13833 (2024-02-02)
Previous clinical reports have shown that capecitabine, an oral prodrug of 5-fluorouracil (5-Fu), can induce peripheral neuropathy, resulting in numbness, paresthesia and hypoesthesia. However, the mechanism through which capecitabine causes peripheral nerve injury remains unclear. Here, we demonstrate that systemic
Yi Shen et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(1), 390-401 (2012-01-06)
Alcohol use disorders (AUDs) constitute the most common form of substance abuse. The development of AUDs involves repeated alcohol use leading to tolerance, alcohol withdrawal syndrome, and physical and psychological dependence, with loss of ability to control excessive drinking. Currently
Zhenzhu Sun et al.
Biochemical pharmacology, 175, 113888-113888 (2020-03-01)
Doxorubicin (DOX) is a powerful anthracycline antineoplastic drug whose clinical application is limited by serious cardiotoxic side effects. Dihydromyricetin (DHM), a flavonoid compound extracted from the Japanese raisin tree (Hovenia dulcis), is cardioprotective in patients with heart failure; however, the
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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