SML3592

GSK3179106

≥98% (HPLC)

• 別名: 2-(4-(4-ethoxy-6-oxo-1,6-dihydropyridin-3-yl)-2-fluorophenyl)-N-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)acetamide
• 実験式（ヒル表記法）: C₂₂H₂₁F₄N₃O₄
• CAS番号: 1627856-64-7
• 分子量: 467.41
• UNSPSCコード: 12352200
• NACRES: NA.21

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: FC(F)(F)C(C)(C)c1[o]nc(c1)NC(=O)Cc2c(cc(cc2)c3c[nH][c](cc3OCC)=O)F
• InChI: 1S/C22H21F4N3O4/c1-4-32-16-9-19(30)27-11-14(16)12-5-6-13(15(23)7-12)8-20(31)28-18-10-17(33-29-18)21(2,3)22(24,25)26/h5-7,9-11H,4,8H2,1-3H3,(H,27,30)(H,28,29,31)
• InChI Key: IDXKJSSOUXWLDB-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

GSK3179106 is a potent and selective gut-restricted RET (Rearranged during transfection) kinase inhibitor. GSK3179106 attenuates abdominal contractions induced by colorectal distention in rat models.

Potent and selective gut-restricted RET (Rearranged during transfection) kinase inhibitor

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable