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アッセイ
≥95% (HPLC)
フォーム
powder
保管条件
protect from light
色
white to light brown
溶解性
DMSO: 20 mg/mL, clear
保管温度
−20°C
InChI
1S/C14H10O2S/c15-11-4-1-9(2-5-11)13-7-10-3-6-12(16)8-14(10)17-13/h1-8,15-16H
InChI Key
MDGWZLQPNOETLH-UHFFFAOYSA-N
生物化学的／生理学的作用
BTC is a selective estrogen receptor (ER) modulator (SERM) that acts as a selective estrogen mimic (SEM).
BTC is a selective estrogen receptor (ER) modulator (SERM) that acts as a selective estrogen mimic (SEM). BTC has been found to be both estrogenic and antiproliferative in ER-positive endocrine-resistant breast cancer cell lines that overexpress protein kinase C alpha (PKCα), which is often associated with tamoxifen resistance. BTC caused regression of endocrine-resistant breast cancer xenografts, and did not support the growth of hormone-dependent xenografts in vivo or cause an increase in uterine weight. As in the case with raloxifene and estradiol, BTC tumor regression was accompanied by the exit of ERα from the nucleus, suggesting extranuclear ERα may be involved in the mehanism of action.
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SML1376-VAR:
SML1376-BULK:
SML1376-10MG:
SML1376-50MG:
最新バージョンのいずれかを選択してください：
Axel X Canatelli et al.
ChemPlusChem, 85(10), 2349-2356 (2020-10-24)
Metal-organic frameworks (MOFs) are known for their versatility in terms of their crystalline structure, porosity, resistance to temperature, radiation damage, and luminescence among others. Gadolinium (Gd) is one of the elements with the highest reported cross-section for low energy neutron
Ho-Young Jang et al.
Environmental pollution (Barking, Essex : 1987), 267, 115583-115583 (2020-12-02)
In this study, a metal organic framework MIL-100(Fe) was synthesized for rhodamine B (RB) removal from aqueous solutions. An experimental design was conducted using a central composite design (CCD) method to obtain the RB adsorption data (n = 30) from batch experiments.
Xiaozhou Huang et al.
Analytical and bioanalytical chemistry, 412(4), 849-860 (2020-01-04)
In this paper, a novel bimetallic Ce-Ni metal-organic frameworks (Ce-Ni-MOF) are synthesized by hydrothermal reaction, using 1,3,5-benzenetricarboxylic acid as a ligand. In particular, the bimetallic Ce-Ni-MOF with the largest specific surface area and catalytic sites was synthesized when the molar
Jibin An et al.
Environmental research, 191, 110067-110067 (2020-08-21)
Metal-organic frameworks (MOFs) are emerging class of porous materials that attracted tremendous attention as eco-friendly photocatalysts. However, poor charge separation in most MOFs largely thwarts their photocatalytic performance. In this work, Materials of Institut Lavoisier-100(Fe) (MIL-100 (Fe)) based on iron
Xinyang Zhang et al.
The Analyst, 145(14), 5011-5018 (2020-06-11)
3D magnetic porous carbon (MPCK) was prepared using the metal-organic framework (MOF) MIL-100(Fe) as the carbon precursor by carbonisation and KOH activation strategies. Carbonisation and activation ensured that MPCK possessed excellent structural and thermal stability, strong magnetic responsiveness and high
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