SML1161

Ki11502

≥98% (HPLC)

• 別名: Ki 11502, N-[[[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]amino]thioxomethyl]-2-methyl-benzamide
• 実験式（ヒル表記法）: C₂₆H₂₃N₃O₄S
• CAS番号: 347155-76-4
• 分子量: 473.54
• MDL番号: MFCD12032139
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825691
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 色: white to brown
• 溶解性: DMSO: 20 mg/mL, clear (warmed)
• 保管温度: 2-8°C
• SMILES記法: S=C(NC(C1=C(C)C=CC=C1)=O)NC(C=C2)=CC=C2OC3=CC=NC4=CC(OC)=C(OC)C=C43
• InChI: 1S/C26H23N3O4S/c1-16-6-4-5-7-19(16)25(30)29-26(34)28-17-8-10-18(11-9-17)33-22-12-13-27-21-15-24(32-3)23(31-2)14-20(21)22/h4-15H,1-3H3,(H2,28,29,30,34)
• InChI Key: ZXGIBSBJQLLUEE-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

Ki11502 is a potent, ATP-competitive multikinase inhibitor that is selective for PDGF receptor. Ki11502 inhibits malignant hematopoietic cells proliferation and induces their apoptosis. Ki11502 is effective against colorectal cancer SW480 cell line.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable