SML0566

VU0359595

≥97% (HPLC)

• 別名: (1R,2R)-N-([S]-1-{4-[5-Bromo-2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxamide
• 実験式（ヒル表記法）: C₂₅H₂₉BrN₄O₂
• CAS番号: 1246303-14-9
• 分子量: 497.43
• MDL番号: MFCD22416858
• UNSPSCコード: 41106300
• PubChem Substance ID: 329825557
• NACRES: NA.77

特性

• アッセイ: ≥97% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 5 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: O=C1N(C2CCN(C[C@H](C)NC([C@H]3[C@H](C4=CC=CC=C4)C3)=O)CC2)C5=CC=C(Br)C=C5N1
• InChI: 1S/C25H29BrN4O2/c1-16(27-24(31)21-14-20(21)17-5-3-2-4-6-17)15-29-11-9-19(10-12-29)30-23-8-7-18(26)13-22(23)28-25(30)32/h2-8,13,16,19-21H,9-12,14-15H2,1H3,(H,27,31)(H,28,32)/t16-,20-,21+/m0/s1
• InChI Key: JSVNNLRZCJAYTQ-ORYQWCPZSA-N

詳細

生物化学的／生理学的作用

VU0359595 is a PLD1 specific inhibitor with an IC₅₀ of 3.7 nM, and 1500-fold selectivity over PLD2 (IC₅₀ = 6.4 μM).

VU0359595 is a PLD1 specific inhibitor.

特徴および利点

This compound is featured on the Phospholipase D page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable