The serotype is OX19.
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由来生物
bacterial (Proteus vulgaris)
品質水準
フォーム
lyophilized powder
精製方法
phenol extraction
不純物
≤3% Protein (Lowry)
色
white to yellow cast
溶解性
water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow
輸送温度
ambient
保管温度
2-8°C
関連するカテゴリー
詳細
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. They consist of lipid A moiety linked to an antigenic O-polysaccharide.
Proteus vulgaris is a rod-shaped Gram-negative, facultative anaerobe bacterium. It inhabits the intestinal tract of humans and animals and can be found in soil, water and feces.[1] P. vulgaris is a member of the Enterobacteriaceae family which are opportunistic pathogens in humans, responsible for urinary tract and burn infections.[2]
The chemical structures of LPS from Proteus sp. are different from each other.
Proteus vulgaris is a rod-shaped Gram-negative, facultative anaerobe bacterium. It inhabits the intestinal tract of humans and animals and can be found in soil, water and feces.[1] P. vulgaris is a member of the Enterobacteriaceae family which are opportunistic pathogens in humans, responsible for urinary tract and burn infections.[2]
The chemical structures of LPS from Proteus sp. are different from each other.
生物化学的／生理学的作用
LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular patterns (PAMPs). Different chemical structures of LPS can be associated with the virulence and pathogenesis of the bacteria.[3][4][5] It has been reported that the LPS chemical structure from P. vulgaris can influence the crystallization of mineral urine components (such as calcium and magnesium), resulting in stone formation in the kidney.[6] Antibodies produced in rickettsial infections were found to react with LPS from Proteus vulgaris and Proteus mirabilis. This phenomenon allows the purified LPS from these two species to serve as a tool for the diagnosis of rickettsiosis (scrub typhus, caused by the bacterium Orientia sp.) in the Weil-Felix test.[7]
その他情報
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SMB00801-25MG:
SMB00801-25MG-PW:
SMB00801-VAR:
SMB00801-BULK:
最新バージョンのいずれかを選択してください：
A Torzewska et al.
FEMS immunology and medical microbiology, 31(3), 227-234 (2001-11-27)
The O-specific polysaccharide (O-antigen) of the lipopolysaccharide (LPS) of Proteus vulgaris O37 was studied by (1)H and (13)C nuclear magnetic resonance spectroscopy before and after O-deacetylation and found to be structurally similar to that of P. vulgaris O46 studied earlier.
LPS/TLR4 signal transduction pathway
Lu, Y.C., Yeh, W.C., Ohashi, P.S.
Cytokine, 42, 145-151 (2008)
S Mizushiri et al.
Microbiology and immunology, 34(2), 121-133 (1990-01-01)
The lipopolysaccharides (LPS) extracted from Proteus strains OX2, OX19, and OXK used as antigens in the Weil-Felix test, were characterized by chemical analysis and SDS-polyacrylamide gel electrophoresis (SDS-PAGE). To separate the O-polysaccharide, core-oligosaccharide, and lipid A moieties, each LPS was
D J HOSSACK
British journal of pharmacology and chemotherapy, 19, 306-312 (1962-10-01)
Ascending urinary tract infections with stone formation have been produced experimentally in rats, using a modification of the method of Vermuelen & Goetz (1954a, b). A zinc disc infected with a culture of Proteus vulgaris was inserted into the bladder
Generation and characterization of a lipopolysaccharide-specific murine monoclonal antibody to Proteus vulgaris OX19
Bakshi, D., Jain, R., Tuteja, U., Batra, H.V.
World Journal of Microbiology & Biotechnology, 23, 817-821 (2007)
資料
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
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What is the serotype of Proteus vulgaris used for this LPS?
1 回答-
役に立ちましたか？
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Which O-antigen does that P.vulgaris come with? And from which strain was the LPS isolated?
1 回答-
The o-antigen is O-polysaccharide. The strain is considered proprietary. Please see the link below for additional information that may be helpful.
https://pubmed.ncbi.nlm.nih.gov/9858461/The link below offers additional information to all of the lectin products, as well as a helpful selection guide:
https://www.sigmaaldrich.com/technical-documents/technical-article/research-and-disease-areas/glycobiology/lectin-selection-guide-useful-guide-for-selecting-right-lectin#lectin役に立ちましたか？
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