SAB5900405

Anti-Monkeypox virus/MPXV A29L Antibody (SAA0286)

• 別名: A29L, Monkeypox virus (MPXV),A29
• UNSPSCコード: 12352203

特性

• 由来生物: mouse
• 品質水準: 100
• リコンビナント: expressed in CHO cells
• 結合体: unconjugated
• 抗体製品の状態: affinity purified immunoglobulin
• クローン: SAA0286, recombinant monoclonal
• フォーム: liquid
• 分子量: 150 kDa
• 化学種の反応性: monkeypox virus
• 濃度: 1 mg/mL
• テクニック: ELISA: 1:2000-1:4000; neutralization: 0.01-10 μg/mL
• 色: colorless
• pH: 7.4
• アイソタイプ: IgG2a, kappa
• タンパク質IDアクセッション番号: NP_536566.1
• UniProtアクセッション番号: Q77HM6
• 輸送温度: wet ice
• 保管温度: -65 to -96°C
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Anti-Monkeypox virus/MPXV A29L Antibody, clone SAA0286, is a monoclonal antibody produced in mouse. It is a single, highly specific, cloned antibody that is directed against the A29L protein of the monkeypox virus. It is composed of two heavy chains and two light chains, linked together by disulfide bonds. The heavy chains contain the antigen-binding region, and the light chains contain the constant region. The antigen-binding region is composed of two variable domains, which are responsible for recognizing and binding to the antigen.


Monkeypox virus (MPXV), like smallpox virus, belongs to the genus Orthopoxvirus. Its morphology is consistent with that of orthopoxvirus, with a brick-shaped or oval shape with rounded corners and a size of 200~400nm. Brick-shaped or oval-shaped, covered by a lipoprotein membrane or envelope, with two protein-containing side bodies in the middle, and a thick membrane core containing a large double-stranded DNA gene body. The genome of Mpox virus is a double-stranded DNA, about 197kb long, and the end of the genome contains an identical but opposite terminal inverted repeat sequence. The virus contains 190 open reading frames, 4 of which are located in terminal inverted repeats. The core proteins of monkeypox virus are A29L, A35R, B6R, M1R, H3L.

特異性

Monoclonal Anti-Monkeypox virus/MPXV A29L Antibody, clone SAA0286 binds to the A29L protein of the monkeypox virus, thereby inhibiting its ability to replicate and spread. This prevents the virus from causing infection and disease. The antibody also has the ability to neutralize the virus, which further prevents it from causing infection.

アプリケーション

ELISA,neutralization

包装

100µg per vial / 1 mg per vial

保管および安定性

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable