Purified recombinant fragment of human PBK expressed in E.coli. Mouse monoclonal antibody raised against PBK
物理的形状
Ascitic fluid containing 0.03% sodium azide.
免責事項
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Molecular imaging and biology, 21(4), 705-712 (2018-10-26)
Lymphokine-activated killer T cell-originated protein kinase (TOPK) is a fairly new cancer biomarker with great potential for clinical applications. The labeling of a TOPK inhibitor with F-18 can be exploited for positron emission tomography (PET) imaging allowing more accurate patient
British journal of cancer, 117(4), 503-512 (2017-07-06)
Tumour-specific radiosensitising treatments may enhance the efficacy of radiotherapy without exacerbating side effects. In this study we determined the radiation response following depletion or inhibition of TOPK, a mitogen-activated protein kinase kinase family Ser/Thr protein kinase that is upregulated in
European journal of nuclear medicine and molecular imaging, 47(4), 1003-1010 (2019-11-18)
OTS514 is a highly specific inhibitor targeting lymphokine-activated killer T cell-originated protein kinase (TOPK). A fluorescently labeled TOPK inhibitor could be used for tumor delineation or intraoperative imaging, potentially improving patient care. Fluorescently labeled OTS514 was obtained by conjugating the
Cell death and differentiation, 28(4), 1333-1346 (2020-11-11)
T-LAK-originated protein kinase (TOPK) overexpression is a feature of multiple cancers, yet is absent from most phenotypically normal tissues. As such, TOPK expression profiling and the development of TOPK-targeting pharmaceutical agents have raised hopes for its future potential in the