SAB4504690

Anti-phospho-Bax (pSer¹⁸⁴) antibody produced in rabbit

affinity isolated antibody

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 21 kDa
• 交差性: mouse, rat, human
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:10000; immunohistochemistry: 1:50-1:100
• NCBIアクセッション番号: Q07812
• UniProtアクセッション番号: Q07812
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer184)
• 遺伝子情報: human ... BAX(581)

詳細

詳細

Bif-1 (BAX-interacting factor 1), a membrane-curvature inducing protein is located on human chromosome 19q13. Bif-1 is also known as SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1)/ Endophilin B1. It belongs to the membrane curvature-driving endophilin protein family.

免疫原

The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Ser184.

Immunogen Range: 143-192

生物化学的／生理学的作用

Bif-1 (BAX-interacting factor 1) plays a vital role in apoptosis. BAX gene may act as a negative regulator of autophagy in CRC (Colorectal cancer) development. Lack of Bif-1 affects lipid homeostasis and results in obesity followed by insulin resistance.

特徴および利点

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物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable