SAB4500662

Anti-Aggrecan (Cleaved-Asp³⁶⁹), N-Terminal antibody produced in rabbit

affinity isolated antibody

• 別名: CSPCP, CSPG1, aggrecan core protein, cartilage-specific proteoglycan core protein, chondroitin sulfate proteoglycan core protein 1
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 44 kDa
• 交差性: human, rat
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBIアクセッション番号: P16112
• UniProtアクセッション番号: P16112
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: proteolytically cleaved (Asp369)
• 遺伝子情報: human ... ACAN(176)

詳細

詳細

Anti-Aggrecan (Cleaved-Asp³⁶⁹) Antibody detects endogenous levels of fragment of activated Aggrecan (Cleaved-Asp³⁶⁹) protein.

Aggrecan is a large aggregating chondroitin sulfate proteoglycan of the human cartilage. It is encoded by AGC1 (aggrecan) gene. It is located on human chromosome 15q26.1.

免疫原

The antiserum was produced against synthesized peptide derived from human Aggrecan.

Immunogen Range: 320-369

アプリケーション

Anti-Aggrecan (Cleaved-Asp369), N-Terminal antibody has been used in western blotting[1][2] and immunostaining.

生物化学的／生理学的作用

Mutations in aggrecan results in autosomal dominant short stature with accelerated skeletal maturation. Mutation in the variable repeat region of the aggrecan gene (AGC1) leads to spondyloepiphyseal dysplasia.

特徴および利点

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物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable