SAB4300672

Anti-phospho-Stat2 (pTyr⁶⁹⁰) antibody produced in rabbit

affinity isolated antibody

• 別名: Anti-ISGF-3, Anti-MGC59816, Anti-P113, Anti-STAT113
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: ~113 kDa
• 交差性: human
• 濃度: 1 mg/mL
• テクニック: western blot: 1:500-1:1000
• アイソタイプ: IgG
• 免疫原配列: (R-K-Yp-L-K)
• NCBIアクセッション番号: NM_005419.3
• UniProtアクセッション番号: P52630
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pTyr690)
• 遺伝子情報: human ... Stat2(6773)

詳細

詳細

The antibody detects endogenous level of Stat2 only when phosphorylated at Tyrosine 690.

免疫原

Peptide sequence around phosphorylation site of tyrosine 690 (R-K-Yp-L-K), according to the protein NP_005410.1

特徴および利点

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ターゲットの説明

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) hasbeen shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable