Anti-FLT41 antibody produced in rabbit, Anti-LMPH1A antibody produced in rabbit, Anti-PCL antibody produced in rabbit, Anti-VEGFR3 antibody produced in rabbit, Anti-fms-related tyrosine kinase 4 antibody produced in rabbit
Fms related tyrosine kinase 4 (FLT4) is also known as vascular endothelial growth factor receptor 3 (VEGFR3). It is expressed in the blood and lymphatic endothelial cells during early development. The gene encoding FLT4 is localized on human chromosome 5q35.3.
免疫原
Peptide sequence around aa. 1279-1283 (L-A-S-E-E), according to the protein FLT4.
アプリケーション
Anti-FLT4 antibody produced in rabbit has been used in immunohistochemistry.
生物化学的／生理学的作用
Fms related tyrosine kinase 4 (FLT4) has a role in lymphangiogenesis and angiogenesis. It acts as an activator in signaling pathways. Mutations in the gene encoding FLT4 have been linked to Milroy disease.
特徴および利点
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ターゲットの説明
Receptor for VEGFC. Has a tyrosine-protein kinase activity.
物理的形状
PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Two anti-angiogenic TKI-PET tracers, [11C]axitinib and [11C]nintedanib: Radiosynthesis, in vivo metabolism and initial biodistribution studies in rodents
Paul S, et al.
Nuclear Medicine and Biology null
A novel FLT4 Gene mutation and MR lymphangiography in a Chinese family with Milroy disease
