SAB4200784

Anti-Cellular Fibronectin antibody, Mouse monoclonal

clone FN-3E2, hybridoma cell culture supernatant

• 別名: Anti-CIG, Anti-Cold-insoluble globulin, Anti-FN
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 抗体製品の状態: culture supernatant
• 抗体製品タイプ: primary antibodies
• クローン: FN-3E2, monoclonal
• フォーム: buffered aqueous solution
• 分子量: ~220-260 kDa
• 交差性: chicken, rat, human, mouse
• テクニック: immunoblotting: suitable; immunofluorescence: 1:2,000-1:4,000 using human foreskin fibroblast Hs68 cells; immunohistochemistry: suitable
• アイソタイプ: IgM
• UniProtアクセッション番号: P02751
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... FN1(2335)

詳細

詳細

Anti-Cellular Fibronectin antibody, Mouse monoclonal (mouse IgM isotype) is derived from the FN-3E2 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mice immunized with the antigens released in culture from a breast cancer cell line. Fibronectin (FN), also known as cold-insoluble globulin (CIG), is an extracellular matrix multi-domain glycoprotein composed of two nearly identical disulphide bound polypeptides. Fibronectin 1 is a glycoprotein, that is coded by FN1 gene. It is expressed in the plasma and at the cell surface. It is mapped to human chromosome 2q35. Cellular fibronectin is produced by various cell types, including fibroblasts, endothelial cells, chondrocytes, synovial cells, and myocytes.

免疫原

Antigens released in culture from a breast cancer cell line

アプリケーション

Anti-Cellular Fibronectin antibody, Mouse monoclonal has been used in:

• immunoblotting
• immunofluorescence
• immunohistochemistry

Anti-cellular Fibronectin antibody, mouse monocloneal has been used in various immunochemical techniques including immunoblotting (220-260 kDa), immunofluorescence, and immunohistochemistry.

生物化学的／生理学的作用

Fibronectin participates in cell adhesion, growth, migration, wound healing, blood coagulation and metastasis. Mutations in FN1 results in glomerulopathy. It plays an important role in cell attachment and spreading, control of cell cytoskeleton, morphology and differentiation. FN1 is also involved in extracellular matrix formation, haemostasis and thrombosis. It is a ubiquitous and essential component of the extracellular matrix (ECM) and plays a vital role in tissue repair mechanism.

物理的形状

The product is supplied as a culture supernatant solution containing 15 mM sodium azide as a preservative. The product contains fetal calf serum.

その他情報

This product is for R&D use only, not for drug, household, or other uses.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable